Figures (3)  Tables (1)

    • Figure 1. 

      Hierarchical clustering of epigenetic concepts: unveiling pathways to agricultural innovation.

    • Figure 2. 

      Exploring approaches for peanut allergy and epigenome editing.

    • Figure 3. 

      Health and economic benefits of allergen-free peanuts.

    • No. Epigenetic editing tools Description summary Ref.
      1 CRISPR/dCas9 (Dead Cas9) Used for targeted gene repression by modifying gene expression without cutting DNA. [49]
      2 Transcription activator Engineered to precisely target DNA sequences for the epigenetic regulation of gene expression. [50,51]
      3 Zinc finger nucleases Engineered proteins that target and bind specific DNA sequences to induce epigenetic changes. [52]
      4 RNA interference Utilizes small RNAs to silence allergenic gene expression at the post-transcriptional level. [53]
      5 DNA Methyltransferase Used to target and methylate specific gene regions, silencing allergenic genes. [54]
      6 Histone deacetylase Employed to alter histone acetylation, repressing allergenic gene expression by tightening chromatin. [55]
      7 CRISPR/Cas13 Used to degrade allergenic transcripts in peanuts. [56]
      8 Non-coding RNA-based tools Regulate the expression of allergenic genes through epigenetic mechanisms. [57]

      Table 1. 

      Epigenetic editing tools that could be applied for allergen-free peanut production.