Figures (6)  Tables (0)

    • Figure 1. 

      Resveratrol alleviates liver damage in weaned piglets with intrauterine growth retardation. (a) Absolute weight of liver, (b) relative weight of liver, (c) serum aspartate aminotransferase (AST) activity, (d) serum alanine aminotransferase (ALT) activity. NC, piglets with normal birth weight fed a basal diet; IC, piglets with intrauterine growth retardation fed a basal diet; IR, piglets with intrauterine growth retardation fed a basal diet supplemented with 300 mg/kg RSV. Results are presented as means and standard errors. * p < 0.05.

    • Figure 2. 

      Resveratrol improves hepatic redox status in weaned piglets with intrauterine growth retardation. (a) MDA, malondialdehyde. (b) T-SOD, total superoxide dismutase. (c) GPX, glutathione peroxidase. (d) GSH, reduced form of glutathione. NC, piglets with normal birth weight fed a basal diet; IC, piglets with intrauterine growth retardation fed a basal diet; IR, piglets with intrauterine growth retardation fed a basal diet supplemented with 300 mg/kg RSV. Results are presented as means and standard errors. * p < 0.05.

    • Figure 3. 

      Resveratrol affects hepatic antioxidant function-related gene expression in weaned piglets with intrauterine growth retardation. (a) GCLM, glutamate-cysteine ligase modifier subunit. (b) GCLC, glutamate-cysteine ligase catalytic subunit. (c) SOD1, superoxide dismutase 1. (d) SOD2, superoxide dismutase 2. (e) GPX1, glutathione peroxidase 1. (f) GPX4, glutathione peroxidase 4. (g) HO1, heme oxygenase 1. (h) NQO1, NAD (P) H: quinone oxoreductase 1. NC, piglets with normal birth weight fed a basal diet; IC, piglets with intrauterine growth retardation fed a basal diet; IR, piglets with intrauterine growth retardation fed a basal diet supplemented with 300 mg/kg RSV. Results are presented as means and standard errors. * p < 0.05.

    • Figure 4. 

      Resveratrol inhibits hepatic inflammation in weaned piglets with intrauterine growth retardation. (a) IL18, interleukin 18. (b) IL1β, interleukin 1 beta. NC, piglets with normal birth weight fed a basal diet; IC, piglets with intrauterine growth retardation fed a basal diet; IR, piglets with intrauterine growth retardation fed a basal diet supplemented with 300 mg/kg RSV. Results are presented as means and standard errors. * p < 0.05.

    • Figure 5. 

      Resveratrol enhances hepatic energy production in weaned piglets with intrauterine growth retardation. (a) ATP, adenosine triphosphate. (b) Complex I. (c) Complex III. (d) Complex V. NC, piglets with normal birth weight fed a basal diet; IC, piglets with intrauterine growth retardation fed a basal diet; IR, piglets with intrauterine growth retardation fed a basal diet supplemented with 300 mg/kg RSV. Results are presented as means and standard errors. * p < 0.05.

    • Figure 6. 

      Resveratrol regulates hepatic mitophagy-related gene expression in weaned piglets with intrauterine growth retardation. (a) Parkin. (b) PINK1, PTEN-induced putative kinase 1. (c) Beclin1. (d) BNIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (e) BNIP3L, BCL2/adenovirus E1B 19-kDa-interacting protein 3-like. (f) OPTN, optineurin. (g) FUNDC1, FUN14 domain-containing 1. (h) p62. (i) Map1lc3α, microtubule-associated protein 1 light chain 3 alpha. NC, piglets with normal birth weight fed a basal diet; IC, piglets with intrauterine growth retardation fed a basal diet; IR, piglets with intrauterine growth retardation fed a basal diet supplemented with 300 mg/kg RSV. Results are presented as means and standard errors. * p < 0.05.