Figures (0)  Tables (4)
    • Parameters The rate of
      always requesting the test      		 OR 95% CI p-Value
      Medical branch
      Medical oncologist 53.3% 1 (reference)
      Surgeon (general surgeon; gynaecologist; urologist) 56.3%
      (69.7; 56.7; 0)      		 1.12 0.6−1.66 0.707
      Medical geneticist 78.8% 3.22 1.3−8.3 0.013
      Years of experience
      0−5 years 51.4% 0.132
      6−10 years 70.0%
      11−20 years 69.7%
      Over 20 years 64.5%
      Institution
      State hospital 48.8% 0.777
      State university 63.6%
      Private hospital/clinic 61.1%
      Private university/foundation 68.8%
      Availability of germline BRCA testing
      Available 62.6% 0.17
      Not available 51.2%
      Test reimbursement
      Covered by SGK 61.9% 0.36
      Private/additional payment 54.3%
      Knowledge level
      Very sufficient/sufficient 72.9% 6.1 3.2−11.7 < 0.001
      Not sufficient 30.6%
      OR, odds ratio; CI, confidence interval; knowledge level (interpreting BRCA test results).

      Table 1. 

      Parameters influencing the rate of always requesting BRCA testing when indicated.

    • Decision-making context Prophylactic mastectomy (n) Prophylactic oophorectomy (n)
      Tumour boards 63 60
      Joint decision with geneticists 37 41
      Multidisciplinary consultations 30 30
      Geneticist-only consultation 10 8
      Individual decisions 66 67

      Table 2. 

      Prophylactic decision-making.

    • Parameters Knowledge level p-Value
      Very sufficient/sufficient (n = 144) Insufficient (n = 62)
      The rate of always recommending screening for BRCA-positive cancer patients 77.1% (111) 40.3% (25) < 0.001
      The rate of always referring relatives of BRCA-positive patients for BRCA testing 19.4% (28) 11.3% (7) 0.013
      The rate of referring relatives of BRCA-positive patients to genetic counseling for BRCA testing 56.9% (82) 45.2% (28)
      The rate of rarely or never referring relatives of BRCA-positive patients for BRCA testing. 23.6% (34) 43.5% (27)

      Table 3. 

      Relationship between level of knowledge on BRCA testing and screening recommendations.

    • Questions All participate Most participate Some participate/
      do not participate
      BRCA-positive patients' participation in screening: 4.9% 51.0% 44.2%
      Is participation regular?
      		 4.9% 46.1% 49%
      Participation of BRCA-positive carriers in screening: 3.4% 35.0% 61.7%
      Is participation regular? 4.4% 35.0% 62.1%
      Always/very frequently Very frequently/frequently Rarely/never
      Rates of prophylactic surgery in BRCA-positive breast cancer patients for ovarian cancer risk 21.4% 40.3% 38.4%
      Rates of prophylactic surgery in BRCA-positive ovarian cancer patients for breast cancer risk 12.7% 39.3% 48.0%
      Rates of prophylactic surgery in BRCA-positive carriers for breast cancer risk 13.6% 28.6% 55.3%
      Rates of prophylactic surgery in BRCA-positive carriers for ovarian cancer risk 16.9% 28.2% 51.9%

      Table 4. 

      Rates of patients and relatives undergoing screening and surgical procedures.