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Figure 1.
Study protocol. All participants underwent group cognitive behavioral therapy (CBT) for smoking cessation. At the beginning of the intervention, the participants were still smokers; they set an individual quitting date between the second and the third CBT session. The exercise sessions started in the same week as the CBT, approximately 2–3 weeks prior to the quitting date of the participants.
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Figure 2.
Consolidated Standards of Reporting Trials (CONSORT) flowchart of study participants' inclusion, randomization, the intervention, and follow-up analyses. ITT, intention to treat; CC, complete cases.
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Figure 3.
Number of completed sport sessions and attendance rates (as a percentage) in the CBT + exercise group. Error bars indicate standard errors of the mean (SE). ITT, intention to treat.
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Figure 4.
Abstinence days for the three time points and the two groups in the ITT sample. Error bars represent 95% confidence intervals around the mean.
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Characteristics Missing (N) Exercise with CBT group (N = 65)
Mean (SD)Missing (N) CBT-only group (N = 67)
Mean (SD)Statistic, p-value Sociodemographics Age 0 38.28 (10.67) 0 39.28 (12.57) t = 0.503, p = 0.621 Gender (female %) 0 56.25% 0 62.69% χ² =1.476; p = 0.487 Years of education* 0 7.15 (1.25) 0 7.22 (1.24) t = 0.310; p = 0.753 Migration background (%) 1 32.81% 0 23.88% χ² = 1.291; p = 0.262 Intelligence (WST) 0 28.36 (4.14) 0 29.81 (3.60) t = 2.149; p = 0.033* Nicotine information Cigarettes per day 0 14.15 (7.03) 0 14.57 (8.50) t = 0.301; p = 0.766 Nicotine dependence (FTND) 0 3.86 (2.01) 0 3.93 (2.47) t = 0.177; p = 0.862 Pack years 0 11.42 (10.62) 0 15.47 (15.98) t = 1.690; p = 0.095 QSU 1 100.89 (30.28) 0 102.63 (32.17) t = 0.318; p = 0.751 WSWS 1 35.18 (16.45) 0 36.075 (13.45) t = 0.339; p = 0.735 Clinical characteristics AUDIT 0 7.06 (4.56) 0 5.49 (4.67) t = –1.947; p = 0.054 ADS-K 0 8.77 (6.70) 0 7.612 (5.52) t = –1.078; p = 0.283 STAI-T 10 39.86 (9.43) 5 38.86 (9.09) t = −0.584; p = 0.561 ASI-3 10 20.67 (12.92) 6 16.56 (10.71) t = −1.865; p = 0.065 Personality characteristics PSS 0 14.34 (6.27) 0 14.34 (5.83) t < 0.001; p = 1.0 PANAS 0 30.28 (5.74)
16.64 (6.39)0 31.76 (5.93)
15.40 (4.85)t = 1.450; p = 0.150
t = −1.253; p = 0.212Barratt impulsiveness scale 10 32.80 (5.70) 5 33.57 (6.61) t = 0.672; p = 0.503 BIS 11 19.83 (3.84) 5 19.62 (3.73) t = −0.292; p = 0.771 BAS 11 41.35 (4.77) 5 40.72 (5.32) t = −0.669; p = 0.505 Other SIMPAQ (total activity)+ 0 5.48 (3.25) 0 5.99 (3.07) t = 0.913; p = 0.363 IPAQ MET total (min/week) 2 3,620.532 (2,254.722) 7 3,329.950 (2,662.031) t = 0.654; p = 0.514 Therapy expectancy/motivation 0 40.73 (5.79) 0 40.43 (7.16) t = −0.264; p = 0.792 F-SozU 11 91.87 (14.97) 7 95.233 (13.79) t = 1.244; p = 0.216 Note: * Years of education refers to years spent in secondary education. Eight years correspond to the German university entrance qualification (Abitur). +Average activity per day in hours (without sleeping and sitting) WST, Wortschatztest, vocabulary-based intelligence; FTND, Fagerstroem Test for Cigarette Dependence; QSU, Questionnaire on Smoking Urges; WSWS, Wisconsin Withdrawal Scale; AUDID, Alcohol Use Disorder Identification Test; ADS-K, German version of the Center for Epidemiological Studies Depression Scale; STAI-T, Spielberger Trait Anxiety Inventory; ASI-3, Anxiety Sensitivity Index-3; PSS, Perceived Stress Scale; PANAS, Positive and Negative Affect Schedule; BIS/BAS, Behavioral Inhibition System and Behavioral Approach System; SIMPAQ, Simple Physical Activity Questionnaire; IPAQ, International Physical Activity Questionnaire, short form; F-SozU, Fragebogen zur Sozialen Unterstützung. Table 1.
Baseline demographic and clinical characteristics of the sample (N = 132).
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N Baseline
mean (SD)N 12 weeks
mean (SD)N 24 weeks
mean (SD)Effect of time Effect of group Interaction of
time × groupSmoking characteristics QSU- craving χ2(2) = 126.229
p < 0.001χ2(1) = 0.072
p = 0.788χ2(2) = 2.571
p = 0.276CBT only 67 102.627 (32.167) 47 54.702 (20.201) 26 69.615 (35.669) CBT + exercise 64 100.891 (30.282) 43 62.977 (24.996) 22 65.409 (30.767) WSWS (withdrawal) χ2(2) = 7.404
p = 0.025χ2(1) = 0.209
p =0.647χ2(2) = 1.364
p = 0.506CBT only 67 35.653 (13.449) 47 32.319 (15.743) 26 36.654 (8.588) CBT + exercise 64 35.100 (16.449) 43 33.558 (13.715) 22 38.273 (11.209) Clinical characteristics ADS-K–depressive symptoms χ2(2) = 17.198
p < 0.001χ2(1) = 0.401
p = 0.526χ2(2) = 0.736
p = 0.692CBT only 67 7.612 (5.516) 47 9.298 (7.018) 27 11.704 (9.380) CBT + exercise 64 8.766 (6.699) 43 9.977 (5.970) 23 10.826 (5.606) Physical activity IPAQ-SF MET total (min/week) χ2(2) = 7.711
p = 0.021χ2(1) = 0.410
p = 0.522χ2(2) = 0.217
p = 0.897CBT only 63 3,620.532 (2,254.722) 44 4,480.170 (2,731.361) 24 4,252.313 (2,652.092) CBT + exercise 60 3,329.950 (2,662.031) 43 4,451.279 (2,884.689) 19 3,833.763 (2,224.601) Note: Not all participants who completed the follow-up assessment interview finished the questionnaires at follow-up. QSU, Questionnaire on Smoking Urges; WSWS, Wisconsin Withdrawal Scale; ADS-K, German version of the Center for Epidemiological Studies Depression Scale; IPAQ, International Physical Activity Questionnaire, short form. Table 2.
Secondary outcome variables across the three time points, separated for the two treatment groups.
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Post-intervention Follow-up Abstinence days r = 0.620 (p = < 0.001) r = 0.528 (p = 0.001) ADS-K r = 0.024 (p = 0.882) r = –0.056 (p = 0.808) QSU r = –0.400 (p = 0.001) r = –0.079 (p = 0.739) WSWS r = –0.045 (p = 0.781) r = 0.294 (p = 0.208) IPAQ r = 0.113 (p = 0.494) r = –0.050 (p = 0.849) Note: The baseline values served as a covariate in the correlation analysis. QSU, Questionnaire on Smoking Urges; WSWS, Wisconsin Withdrawal Scale; ADS-K, German version of the Center for Epidemiological Studies Depression Scale; IPAQ, International Physical Activity Questionnaire, short form. Table 3.
Pearson correlation analysis between number of completed sport sessions with abstinence days, depressive symptoms (ADS-K), craving (QSU), withdrawal (WSWS), and physical activity levels (IPAQ-SF) within the sports group using the CC sample only (n = 37).
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Tables
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