| [1] |
Yang Y, Grossart HP. 2024. Antibiotic resistance genes: a global change factor. |
| [2] |
Kalashnikov M, Mueller M, McBeth C, Lee JC, Campbell J, et al. 2017. Rapid phenotypic stress-based microfluidic antibiotic susceptibility testing of Gram-negative clinical isolates. |
| [3] |
Fenical W, Jensen PR. 2006. Developing a new resource for drug discovery: marine actinomycete bacteria. |
| [4] |
Li K, Zhu Y, Shi X, Yan M, Li J, et al. 2024. Effects of Zn and oxytetracycline on mobile genetic elements, antibiotic resistance genes, and microbial community evolution in soil. |
| [5] |
Wang X, Lan B, Fei H, Wang S, Zhu G. 2021. Heavy metal could drive co-selection of antibiotic resistance in terrestrial subsurface soils. |
| [6] |
Song L, Jiang G, Wang C, Ma J, Chen H. 2022. Effects of antibiotics consumption on the behavior of airborne antibiotic resistance genes in chicken farms. |
| [7] |
Song L, Wang C, Jiang G, Ma J, Li Y, et al. 2021. Bioaerosol is an important transmission route of antibiotic resistance genes in pig farms. |
| [8] |
Tiseo K, Huber L, Gilbert M, Robinson TP, Van Boeckel TP. 2020. Global trends in antimicrobial use in food animals from 2017 to 2030. |
| [9] |
Sarmah AK, Meyer MT, Boxall ABA. 2006. A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. |
| [10] |
Gaballah MS, Guo J, Sun H, Aboagye D, Sobhi M, et al. 2021. A review targeting veterinary antibiotics removal from livestock manure management systems and future outlook. |
| [11] |
Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, et al. 2019. Definitions and guidelines for research on antibiotic persistence. |
| [12] |
Zhou L, Li S, Li F. 2022. Damage and elimination of soil and water antibiotic and heavy metal pollution caused by livestock husbandry. |
| [13] |
Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, et al. 2019. Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans. |
| [14] |
Yang Y, Xing S, Chen Y, Wu R, Wu Y, et al. 2021. Profiles of bacteria/phage-comediated ARGs in pig farm wastewater treatment plants in China: association with mobile genetic elements, bacterial communities and environmental factors. |
| [15] |
Yue Z, Zhang J, Zhou Z, Ding C, Wan L, et al. 2021. Pollution characteristics of livestock faeces and the key driver of the spread of antibiotic resistance genes. |
| [16] |
He Y, Yuan Q, Mathieu J, Stadler L, Senehi N, et al. 2020. Antibiotic resistance genes from livestock waste: occurrence, dissemination, and treatment. |
| [17] |
Huygens J, Rasschaert G, Heyndrickx M, Dewulf J, Van Coillie E, et al. 2022. Impact of fertilization with pig or calf slurry on antibiotic residues and resistance genes in the soil. |
| [18] |
Ahmed I, Zhang Y, Sun P, Xie Y, Zhang B. 2023. Sensitive response mechanism of ARGs and MGEs to initial designed temperature during swine manure and food waste co-composting. |
| [19] |
Wang B, Song L, Li W, Hou La, Li J, et al. 2023. Distribution and migration of antibiotic resistance genes, as well as their correlation with microbial communities in swine farm and its surrounding environments. |
| [20] |
Baker-Austin C, Wright MS, Stepanauskas R, McArthur JV. 2006. Co-selection of antibiotic and metal resistance. |
| [21] |
Gao FZ, He LY, He LX, Zou HY, Zhang M, et al. 2020. Untreated swine wastes changed antibiotic resistance and microbial community in the soils and impacted abundances of antibiotic resistance genes in the vegetables. |
| [22] |
Xu B, Zhang Y, He Y. 2023. The current situation of water pollutants and pollution source in Poyang Lake: a review. |
| [23] |
Ding H, Qiao M, Zhong J, Zhu Y, Guo C, et al. 2020. Characterization of antibiotic resistance genes and bacterial community in selected municipal and industrial sewage treatment plants beside Poyang Lake. |
| [24] |
Zhu YG, Johnson TA, Su JQ, Qiao M, Guo GX, et al. 2013. Diverse and abundant antibiotic resistance genes in Chinese swine farms. |
| [25] |
Liu W, Qian J, Ding H, Li J, Liu J, et al. 2024. Synergistic interactions of light and dark biofilms in rotating algal biofilm system for enhanced aquaculture wastewater treatment. |
| [26] |
Zhang Z, Zhang Q, Wang T, Xu N, Lu T, et al. 2022. Assessment of global health risk of antibiotic resistance genes. |
| [27] |
Eliyan C, McConville J, Zurbrügg C, Koottatep T, Sothea K, et al. 2024. Heavy metal contamination of faecal sludge for agricultural production in Phnom Penh, Cambodia. |
| [28] |
Hou D, Jia X, Wang L, McGrath SP, Zhu YG, et al. 2025. Global soil pollution by toxic metals threatens agriculture and human health. |
| [29] |
National Environmental Protection Agency (National Environmental Protection Agency). 1990. 中国土壤元素背景值[Soil Element background values in China]. 中国环境科学出版社 [China Environment Publishing Group], China. pp. 329−493 (In Chinese) |
| [30] |
Liu C, Feng C, Duan Y, Wang P, Peng C, et al. 2023. Ecological risk under the dual threat of heavy metals and antibiotic resistant Escherichia coli in swine-farming wastewater in Shandong Province, China. |
| [31] |
Gourlez E, Beline F, Dourmad JY, Monteiro AR, Guiziou F, et al. 2024. The fate of Cu and Zn along the feed-animal-excreta-effluent continuum in swine systems according to feed and effluent treatment strategies. |
| [32] |
Błażejewska A, Zalewska M, Grudniak A, Popowska M. 2022. A comprehensive study of the microbiome, resistome, and physical and chemical characteristics of chicken waste from intensive farms. |
| [33] |
Poach ME, Hunt PG, Reddy GB, Stone KC, Johnson MH, et al. 2007. Effect of intermittent drainage on swine wastewater treatment by marsh–pond–marsh constructed wetlands. |
| [34] |
Partridge SR, Tsafnat G, Coiera E, Iredell JR. 2009. Gene cassettes and cassette arrays in mobile resistance integrons. |
| [35] |
Dawangpa A, Lertwatcharasarakul P, Ramasoota P, Boonsoongnern A, Ratanavanichrojn N, et al. 2021. Genotypic and phenotypic situation of antimicrobial drug resistance of Escherichia coli in water and manure between biogas and non-biogas swine farms in central Thailand. |
| [36] |
Zagui GS, de Almeida OGG, Moreira NC, Silva NGA, Meschede MSC, et al. 2024. Hospital wastewater as source of human pathogenic bacteria: a phenotypic and genomic analysis of international high-risk clone VIM-2-producing Pseudomonas aeruginosa ST235/O11. |
| [37] |
Lu Y, Wang J, Wang X, Meng X, Yan S, et al. 2022. Sludge conditioning treatments impact the fate of antibiotic resistance genes in agricultural soils amended with sludge composts. |
| [38] |
Zhou SYD, Wei MY, Giles M, Neilson R, Zheng F, et al. 2020. Prevalence of antibiotic resistome in ready-to-eat salad. |
| [39] |
Wang H, Wang X, Zhang L, Zhang X, Cao Y, et al. 2024. Meta-analysis addressing the potential of antibiotic resistance gene elimination through aerobic composting. |
| [40] |
Zhao K, Yin X, Wang N, Chen N, Jiang Y, et al. 2024. Optimizing the management of aerobic composting for antibiotic resistance genes elimination: a review of future strategy for livestock manure resource utilization. |
| [41] |
Wang G, Li G, Chang J, Kong Y, Jiang T, et al. 2021. Enrichment of antibiotic resistance genes after sheep manure aerobic heap composting. |
| [42] |
Keenum I, Williams RK, Ray P, Garner ED, Knowlton KF, et al. 2021. Combined effects of composting and antibiotic administration on cattle manure–borne antibiotic resistance genes. |
| [43] |
Liao H, Lu X, Rensing C, Friman VP, Geisen S, et al. 2018. Hyperthermophilic composting accelerates the removal of antibiotic resistance genes and mobile genetic elements in sewage sludge. |
| [44] |
Luisa de Castro e Silva H, Ghysels S, Robles-Aguilar AA, Akyol Ç, Ronsse F, et al. 2024. Hydrothermal carbonisation of manure-derived digestates: chemical properties and heavy metals distribution in end-products. |
| [45] |
Ipiales RP, Lelli G, Diaz E, Diaz-Portuondo E, Mohedano AF, et al. 2024. Study of two approaches for the process water management from hydrothermal carbonization of swine manure: anaerobic treatment and nutrient recovery. |
| [46] |
He Y, Zhao X, Zhu S, Yuan L, Li X, et al. 2023. Conversion of swine manure into biochar for soil amendment: efficacy and underlying mechanism of dissipating antibiotic resistance genes. |
| [47] |
Li K, Rahman SU, Rehman A, Li H, Hui N, et al. 2025. Shaping rhizocompartments and phyllosphere microbiomes and antibiotic resistance genes: the influence of different fertilizer regimes and biochar application. |
| [48] |
Wang X, Zhang L, Gu J, Feng Y, He K, et al. 2023. Effects of soil solarization combined with manure-amended on soil ARGs and microbial communities during summer fallow. |
| [49] |
Duan M, Gu J, Wang X, Li Y, Zhang R, et al. 2019. Factors that affect the occurrence and distribution of antibiotic resistance genes in soils from livestock and poultry farms. |
| [50] |
Li R, Li S, Yan Y, Xie Y, Zhao J, et al. 2025. Mitigating the health risk of antibiotic resistance genes through reductive soil disinfestation in protected agroecosystems. |
| [51] |
Xu F, Guan J, Zhou Y, Song Z, Shen Y, et al. 2023. Effects of freeze-thaw dynamics and microplastics on the distribution of antibiotic resistance genes in soil aggregates. |
| [52] |
Wu Y, Li S, Yu K, Hu J, Chen Q, et al. 2023. Wastewater treatment plant effluents exert different impacts on antibiotic resistome in water and sediment of the receiving river: metagenomic analysis and risk assessment. |
| [53] |
Li YJ, Yuan Y, Tan WB, Xi BD, Wang H, et al. 2024. Antibiotic resistance genes and heavy metals in landfill: a review. |
| [54] |
Liu C, Li B, Wu B, Lin H, Jiang L, et al. 2022. How heavy metal stress promotes dissemination of antibiotic resistance genes in the activated sludge process. |
| [55] |
Yu MF, Chen L, Liu G, Liu W, Yang Y, et al. 2025. Metagenomic deciphers the mobility and bacterial hosts of antibiotic resistance genes under antibiotics and heavy metals co-selection pressures in constructed wetlands. |
| [56] |
Stepanauskas R, Glenn TC, Jagoe CH, Tuckfield RC, Lindell AH, et al. 2006. Coselection for microbial resistance to metals and antibiotics in freshwater microcosms. |
| [57] |
Li L, Liu X, Li J, Chen Z, Song T, et al. 2024. Mitigating Tetracycline antibiotic contamination in chicken manure using ex situ fermentation system. |
| [58] |
dos Santos Lopes E, Ferreira Santaren KC, Araujo de Souza LC, Parente CET, Picão RC, et al. 2024. Cross-environmental cycling of antimicrobial resistance in agricultural areas fertilized with poultry litter: a one health approach. |
| [59] |
Liebert CA, Hall RM, Summers AO. 1999. Transposon Tn21, flagship of the floating genome. |
| [60] |
Chapman JS. 2003. Disinfectant resistance mechanisms, cross-resistance, and co-resistance. |
| [61] |
Ni Z, Gong Z, Song L, Jia C, Zhang X. 2024. Adaptation strategies and functional transitions of microbial community in pyrene-contaminated soils promoted by lead with Pseudomonas veronii and its extracellular polymeric substances. |
| [62] |
Guo X, Qi Z, Li J, Tong H, Ren N, et al. 2024. Overlooked volcanic effect during transmission of antibiotic resistance genes induced by copper and zinc. |
| [63] |
Wei H, Wu X, Chen A, Liu K, Lv Z, et al. 2025. Reserve and proliferation characteristics of antibiotic resistance genes and heavy metal resistance genes in the sewage pipe biofilm under the stress of Cu and Zn. |
| [64] |
Li W, Zhang WG, Zhang MS, Lei ZF, Li PF, et al. 2022. Environmentally relevant concentrations of mercury facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes. |
| [65] |
Hu HW, Wang JT, Li J, Shi XZ, Ma YB, et al. 2016. Long-term nickel contamination increases the occurrence of antibiotic resistance genes in agricultural soils. |