[1]

Tetali SD. 2019. Terpenes and isoprenoids: a wealth of compounds for global use. Planta 249:1−8

doi: 10.1007/s00425-018-3056-x
[2]

Maaz M, Sultan MT, Khalid MU, Raza H, Imran M, et al. 2025. A comprehensive review on the molecular mechanism of lycopene in cancer therapy. Food Science & Nutrition 13:e70608

doi: 10.1002/fsn3.70608
[3]

López-Solís R, Castro-Barquero S, Donat-Vargas C, Corrado M, Arancibia-Riveros C, et al. 2025. Lycopene intake and prostate cancer risk in men at high cardiovascular risk: a prospective cohort study. BMC Medicine 23:627

doi: 10.1186/s12916-025-04440-0
[4]

Moran NE, Thomas-Ahner JM, Wan L, Zuniga KE, Erdman JW, et al. 2022. Tomatoes, lycopene, and prostate cancer: what have we learned from experimental models? The Journal of Nutrition 152:1381−1403

doi: 10.1093/jn/nxac066
[5]

Sharifi-Zahabi E, Soltani S, Malekahmadi M, Rezavand L, Clark CCT, et al. 2022. The effect of lycopene supplement from different sources on prostate specific antigen (PSA): a systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine 64:102801

doi: 10.1016/j.ctim.2022.102801
[6]

Kulawik A, Cielecka-Piontek J, Zalewski P. 2023. The importance of antioxidant activity for the health-promoting effect of lycopene. Nutrients 15:3821

doi: 10.3390/nu15173821
[7]

Khan UM, Sevindik M, Zarrabi A, Nami M, Ozdemir B, et al. 2021. Lycopene: food sources, biological activities, and human health benefits. Oxidative Medicine and Cellular Longevity 2021:2713511

doi: 10.1155/2021/2713511
[8]

Li L, Liu Z, Jiang H, Mao X. 2020. Biotechnological production of lycopene by microorganisms. Applied Microbiology and Biotechnology 104:10307−10324

doi: 10.1007/s00253-020-10967-4
[9]

Nie X, Zuo Z, Zhou L, Gao Z, Cheng L, et al. 2024. Investigating the effect of high-voltage electrostatic field (HVEF) treatment on the physicochemical characteristics, bioactive substances content, and shelf life of tomatoes. Foods 13:2823

doi: 10.3390/foods13172823
[10]

Moroz P, Bartusiak A, Niewiadomska J, Szymański K, Janek T, et al. 2025. Advances in lycopene production: from natural sources to microbial synthesis using Yarrowia lipolytica. Molecules 30:4321

doi: 10.3390/molecules30214321
[11]

Li M, Xia Q, Zhang H, Zhang R, Yang J. 2020. Metabolic engineering of different microbial hosts for lycopene production. Journal of Agricultural and Food Chemistry 68:14104−14122

doi: 10.1021/acs.jafc.0c06020
[12]

Ren J, Shen J, Thai TD, Kim MG, Lee SH, et al. 2023. Evaluation of various Escherichia coli strains for enhanced lycopene production. Journal of Microbiology and Biotechnology 33:973−979

doi: 10.4014/jmb.2302.02003
[13]

Boghigian BA, Salas D, Ajikumar PK, Stephanopoulos G, Pfeifer BA. 2012. Analysis of heterologous taxadiene production in K- and B-derived Escherichia coli. Applied Microbiology and Biotechnology 93:1651−1661

doi: 10.1007/s00253-011-3528-4
[14]

Yoon SH, Lee SH, Das A, Ryu HK, Jang HJ, et al. 2009. Combinatorial expression of bacterial whole mevalonate pathway for the production of β-carotene in E. coli. Journal of Biotechnology 140:218−226

doi: 10.1016/j.jbiotec.2009.01.008
[15]

Liang Z, Zhi H, Fang Z, Zhang P. 2021. Genetic engineering of yeast, filamentous fungi and bacteria for terpene production and applications in food industry. Food Research International 147:110487

doi: 10.1016/j.foodres.2021.110487
[16]

Banerjee A, Wu Y, Banerjee R, Li Y, Yan H, et al. 2013. Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway. Journal of Biological Chemistry 288:16926−16936

doi: 10.1074/jbc.M113.464636
[17]

Hu B, Zhou J, Li J, Chen J, Du G, et al. 2025. Efficient biosynthesis of furanocoumarin intermediate marmesin by engineered Escherichia coli. ACS Synthetic Biology 14:954−966

doi: 10.1021/acssynbio.4c00892
[18]

Li Y, Wang G. 2016. Strategies of isoprenoids production in engineered bacteria. Journal of Applied Microbiology 121:932−940

doi: 10.1111/jam.13237
[19]

Raghavan I, Juman R, Wang ZQ. 2024. The non-mevalonate pathway requires a delicate balance of intermediates to maximize terpene production. Applied Microbiology and Biotechnology 108:245

doi: 10.1007/s00253-024-13077-7
[20]

Rehman E, Hawaibam BS, Nguyen MP, Wang C, Yoon SH, et al. 2025. Enhancing lycopene production in Bacillus subtilis by overcoming a critical enzymatic bottleneck. Frontiers in Bioengineering and Biotechnology 13:1670015

doi: 10.3389/fbioe.2025.1670015
[21]

Ajikumar PK, Xiao WH, Tyo KEJ, Wang Y, Simeon F, et al. 2010. Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli. Science 330:70−74

doi: 10.1126/science.1191652
[22]

Perez-Gil J, Behrendorff J, Douw A, Vickers CE. 2024. The methylerythritol phosphate pathway as an oxidative stress sense and response system. Nature Communications 15:5303

doi: 10.1038/s41467-024-49483-8
[23]

Liu CL, Dong HG, Xue K, Sun L, Yang Y, et al. 2022. Metabolic engineering mevalonate pathway mediated by RNA scaffolds for mevalonate and isoprene production in Escherichia coli. ACS Synthetic Biology 11:3305−3317

doi: 10.1021/acssynbio.2c00226
[24]

Wang Y, Yu J, Zhang H, Xu M, Liu Q, et al. 2025. Shaping up a mevalonate pathway in the E. coli–E. coli coculture system for the production of sesquiterpenes. Journal of Agricultural and Food Chemistry 73:4820−4828

doi: 10.1021/acs.jafc.4c12483
[25]

Li M, Chen H, Liu C, Guo J, Xu X, et al. 2019. Improvement of isoprene production in Escherichia coli by rational optimization of RBSs and key enzymes screening. Microbial Cell Factories 18:4

doi: 10.1186/s12934-018-1051-3
[26]

Yang L, Wang C, Zhou J, Kim SW. 2016. Combinatorial engineering of hybrid mevalonate pathways in Escherichia coli for protoilludene production. Microbial Cell Factories 15:14

doi: 10.1186/s12934-016-0409-7
[27]

Zhu X, Wu Y, Lv X, Liu Y, Du G, et al. 2022. Combining CRISPR–Cpf1 and recombineering facilitates fast and efficient genome editing in Escherichia coli. ACS Synthetic Biology 11:1897−1907

doi: 10.1021/acssynbio.2c00041
[28]

Hussain MH, Hong Q, Zaman WQ, Mohsin A, Wei Y, et al. 2021. Rationally optimized generation of integrated Escherichia coli with stable and high yield lycopene biosynthesis from heterologous mevalonate (MVA) and lycopene expression pathways. Synthetic and Systems Biotechnology 6:85−94

doi: 10.1016/j.synbio.2021.04.001
[29]

Wei Y, Mohsin A, Hong Q, Guo M, Fang H. 2018. Enhanced production of biosynthesized lycopene via heterogenous MVA pathway based on chromosomal multiple position integration strategy plus plasmid systems in Escherichia coli. Bioresource Technology 250:382−389

doi: 10.1016/j.biortech.2017.11.035
[30]

Yoon SH, Lee YM, Kim JE, Lee SH, Lee JH, et al. 2006. Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate. Biotechnology and Bioengineering 94:1025−1032

doi: 10.1002/bit.20912
[31]

Yang C, Gao X, Jiang Y, Sun B, Gao F, et al. 2016. Synergy between methylerythritol phosphate pathway and mevalonate pathway for isoprene production in Escherichia coli. Metabolic Engineering 37:79−91

doi: 10.1016/j.ymben.2016.05.003
[32]

Rinaldi MA, Ferraz CA, Scrutton NS. 2022. Alternative metabolic pathways and strategies to high-titre terpenoid production in Escherichia coli. Natural Product Reports 39:90−118

doi: 10.1039/d1np00025j
[33]

Niu FX, Lu Q, Bu YF, Liu JZ. 2017. Metabolic engineering for the microbial production of isoprenoids: carotenoids and isoprenoid-based biofuels. Synthetic and Systems Biotechnology 2:167−175

doi: 10.1016/j.synbio.2017.08.001
[34]

Liu N, Liu B, Wang G, Soong YV, Tao Y, et al. 2020. Lycopene production from glucose, fatty acid and waste cooking oil by metabolically engineered Escherichia coli. Biochemical Engineering Journal 155:107488

doi: 10.1016/j.bej.2020.107488
[35]

Tan JC, Hu Q, Scrutton NS. 2024. A growth-coupling strategy for improving the stability of terpenoid bioproduction in Escherichia coli. Microbial Cell Factories 23:279

doi: 10.1186/s12934-024-02548-1