Figures (3)  Tables (3)
    • Figure 1. 

      Graphical representation of all proteins expressed by A. terreus (#NIOSN-SK56-S52) %.

    • Figure 2. 

      Distribution of proteins expressed by A. terreus (#NIOSN-SK56-S52) under 0, 35, and 100 PSU salinity.

    • Figure 3. 

      Mechanism of metal tolerance by A. terreus (#NIOSN-SK56-S52) under salinity and chromium stress.

    • Protein name NCBI gi Function Protein name NCBI gi Function
      40S ribosomal protein S0 114194180 Translation Hexokinase 114191625 Glycolysis/gluconeogenesis
      6-phosphogluconate dehydrogenase 114191912 Pentose phosphate pathway Histone H2A 114189434 Pyrimidine metabolism
      Adenosylhomocysteinase 114197109 Cysteine and methionine metabolism Histone H2B 114189435 Pyrimidine metabolism
      ADP, ATP carrier protein 114194661 Mitochondrial biogenesis Inorganic pyrophosphatase 114196689 Oxidative phosphorylation
      Alcohol dehydrogenase I 114188844 Glycolysis/gluconeogenesis Ketol-acid reductoisomerase, mp 114195083 Valine, leucine and isoleucine biosynthesis
      Aldehyde dehydrogenase 114192389 Ascorbate and aldarate metabolism L-xylulose reductase 114195667 Pentose and glucuronate interconversions
      ATP synthase alpha chain, mp 114193514 Oxidative phosphorylation Malate dehydrogenase, mp 114191202 Carbohydrate metabolism
      ATP synthase beta chain, mitochondrial precursor 114190171 Oxidative phosphorylation Mitochondrial peroxiredoxin PRX1 114192711 Glutathione metabolism/
      stress response
      ATP-citrate synthase subunit 1 114195637 Citrate cycle (TCA cycle) Mitochondrial phosphate carrier protein 114197783 Pantothenate and CoA biosynthesis
      Bacterial hemoglobin 114195409 Uncharacterised Mitochondrial processing peptidase beta subunit 114197569 Folding, sorting and degradation
      Cell division cycle protein 48 114187782 Meiosis Nucleoside diphosphate kinase 114189539 Purine metabolism
      Cerevisin precursor 114191390 Autophagy Outer mitochondrial membrane protein porin 114192911 Mitochondrial biogenesis
      Citrate synthase, mp 114189463 Citrate cycle (TCA cycle) Phosphoglycerate kinase 114197170 Glycolysis/gluconeogenesis
      Cytochrome c oxidase polypeptide IV, mp 114188084 Oxidative phosphorylation Pyruvate decarboxylase 114193380 Glycolysis/gluconeogenesis
      Cytochrome c oxidase polypeptide VI, mp 114188679 Oxidative phosphorylation Pyruvate kinase 114193787 Glycolysis/gluconeogenesis
      DNA damage checkpoint protein rad24 114188055 Stress/ DNA repair S-adenosylmethionine synthetase 114197201 Cysteine and methionine metabolism
      Elongation factor 1-beta 114197267 Translation Superoxide dismutase, mp 114191387 Response to oxidative stress
      Elongation factor 2 114196384 Translation Thioredoxin 114190288 Response to oxidative stress
      Enolase 114194476 Glycolysis / Gluconeogenesis Transaldolase 114191388 Carbohydrate metabolism
      Eukaryotic initiation factor 4A 114196711 Translation Transketolase 1 114197498 Carbohydrate metabolism
      Eukaryotic translation initiation factor 5A 114193909 Translation Triosephosphate isomerase 114192224 Carbohydrate metabolism
      Glucose-6-phosphate isomerase 114193156 Carbohydrate metabolic process Tubulin alpha-1 chain 114193585 Transport and catabolism
      Glyceraldehyde-3-phosphate dehydrogenase 540849772 Carbohydrate metabolic process Tubulin beta chain 114197233 Transport and catabolism
      GTP-binding nuclear protein GSP1/Ran 114194939 Signal transduction UDP-glucose 4-epimerase 114190193 Carbohydrate metabolism
      Heat shock 70 kDa protein 114187927 Stress response Vacuolar protease A precursor 114193423 Fungal-type cell wall organization
      Heat shock protein 82 114189469 Stress response Woronin body major protein 114191425 Translation
      Heat shock protein SSC1, mp 114193179 Stress response
      mp = mitochondrial precursor.

      Table 1. 

      Commonly expressed proteins across all salinities and Cr (VI) concentrations by A. terreus.

    • Condition Protein name NCBI gi Function
      0 PSU, 0 mg/L ATP-dependent RNA helicase DOB1 114192864 Spliceosome
      Cystathionine beta-lyase 114195508 Cysteine and methionine metabolism
      Glycolipid-anchored surface protein 5 precursor 114189622 Glycan biosynthesis and metabolism
      Guanine nucleotide-binding protein beta subunit 114195314 Transport and catabolism
      Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial precursor 114191417 Valine, leucine, and isoleucine degradation
      Molybdenum cofactor biosynthesis protein 1 B 114192533 Folding, sorting, and degradation
      Vacuolar ATP synthase subunit B 114196357 Autophagy
      0 PSU, 100 mg/L Allergen Asp f 7 114192930 TNF signaling pathway
      Alternative oxidase, mitochondrial precursor 114190002 Oxidative phosphorylation
      Arabinan endo-1,5-alpha-L-arabinosidase A precursor 114193790 carbohydrate metabolic process
      ATP-dependent protease La 114196169 Cell growth and death
      DNA-directed RNA polymerase II 45 kDa polypeptide 114196335 Transcription
      Quinate permease 114190347 Quinate metabolism
      0 PSU, 500 mg/L Anthranilate synthase component II 114197450 Phenylalanine, tyrosine, and tryptophan biosynthesis
      Endochitinase 1 precursor 114194948 Starch and sucrose metabolism
      Glycerol-3-phosphate dehydrogenase, mitochondrial precursor 114193625 carbohydrate metabolic process
      Nonhistone chromosomal protein 6A 114193442 Replication and repair
      Orotate phosphoribosyltransferase 114196505 Pyrimidine metabolism
      Proliferating cell nuclear antigen 114195863 DNA replication
      Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 1 isoform 114188660 Cell cycle
      Signal recognition particle 54 kDa protein 114189491 Folding, sorting, and degradation
      Transcriptional repressor rco-1 114191721 Transcription
      Vacuolar ATP synthase subunit E 114190926 Oxidative phosphorylation
      WD-repeat protein mip1 114190613 cellular senescence
      35 PSU, 0 mg/L 26S proteasome regulatory subunit rpn-1 114195360 Proteosome
      3-methyl-2-oxobutanoate hydroxymethyltransferase 114191519 Pantothenate and CoA biosynthesis
      Alpha,alpha-trehalose-phosphate synthase 1 114194901 Starch and sucrose metabolism
      Catalase 114196544 Stress response
      cell differentiation protein rcd1 114194699 Meiosis
      Chromosome segregation protein sudA 114196456 Meiosis
      CURS1 443610053 Biosynthesis of secondary metabolites
      Nonsense-mediated mRNA decay protein 3 114194516 Translation
      Nonspecific lipid-transfer protein, mitochondrial precursor 114192954 Lipid metabolism
      Protein kinase lkh1 114192486 MAPK signaling pathway
      35 PSU, 100 mg/L 1,4-alpha-glucan branching enzyme 114190170 Starch and sucrose metabolism
      Coatomer beta subunit 114197239 Oxidative phosphorylation
      Inner membrane magnesium transporter MRS2, mitochondrial precursor 114190882 Metal ion transmembrane transporter activity
      Inositol-3-phosphate synthase 114189610 phosphatidylinositol signaling system
      NADH-ubiquinone oxidoreductase 21 kDa subunit 114196031 Oxidative phosphorylation
      Pre-mRNA splicing factor CLF1 114197157 Transcription
      Zinc-regulated transporter 1 114193659 Transcription factors
      35 PSU, 500 mg/L 26S protease regulatory subunit 8 114196020 Proteosome
      Activator 1 subunit 3 114188298 Folding, sorting, and degradation
      Alanyl-tRNA synthetase 114196954 Aminoacyl-tRNA biosynthesis
      C-1-tetrahydrofolate synthase, mitochondrial precursor 114196661 Folate biosynthesis
      Cholinesterase 114195928 Glycerophospholipid metabolism
      Iron sulfur assembly protein 1 114194102 Biotin metabolism
      Lactoylglutathione lyase 114191927 Pyruvate metabolism
      Methionine aminopeptidase 2B 114192909 Fructose and mannose metabolism
      NAD-dependent histone deacetylase SIR2 114193955 Metabolism of cofactors and vitamins
      Nucleolar GTP-binding protein 2 114192691 Translation
      Splicing factor 3B subunit 3 114194961 Spliceosome
      T-complex protein 1 subunit delta 114193665 Chaperones and folding catalysts
      Transcription initiation factor TFIID subunit 12 114189293 Transcription
      100 PSU, 0 mg/L 3-hydroxy-3-methylglutaryl-coenzyme A reductase 114188011 Melavonate pathway/terpenoid synthesis
      Ankyrin repeat protein nuc-2 114191665 Toll and Imd signaling pathway
      Argininosuccinate lyase 114196749 Arginine biosynthesis
      Aryl-alcohol dehydrogenase 114196508 Tyrosine metabolism
      Casein kinase I isoform epsilon 114190610 Ribosome biogenesis in eukaryotes
      Chitin synthase 6 114196376 Amino sugar and nucleotide sugar metabolism
      Dual specificity tyrosine-phosphorylation regulated kinase 2 114189670 MAPK signaling pathway
      100 PSU, 0 mg/L Mannose-6-phosphate isomerase 114197475 Fructose and mannose metabolism
      Peroxisomal biogenesis factor 6 114196745 Transport and catabolism
      Proteasome subunit alpha type 1 114190652 Folding, sorting, and degradation
      Serine/threonine-protein kinase CLA4 114188881 Cell cycle
      Two-component signaling kinase TcsC 421994880 Signal transduction
      Vacuolar ATP synthase 98 kDa subunit 114194052 Oxidative phosphorylation
      100 PSU, 100 mg/L Aldo-keto reductase yakc 114195515 Arachidonic acid metabolism
      Calcium-transporting ATPase 1 114191621 Calcium signaling pathway
      Cytochrome c oxidase polypeptide V, mitochondrial precursor 114190172 Oxidative phosphorylation
      DNA repair and recombination protein RAD54 114188055 Stress/ DNA repair
      Enoyl-CoA hydratase, mitochondrial precursor 114196542 Fatty acid elongation
      G2/mitotic-specific cyclin cdc13 114195591 Cell cycle
      Glutaryl-CoA dehydrogenase, mitochondrial precursor 114189298 Lipid metabolism
      GTP-binding protein 1 114195273 Signal transduction
      Maleylacetate reductase 114193824 Chlorocyclohexane and chlorobenzene degradation
      Peroxidase/catalase 2 114189895 Stress response
      Phosphoribosylglycinamide formyltransferase 114196550 Purine metabolism
      T-complex protein 1 subunit alpha 114195604 Chaperones and folding catalysts
      Threonine synthase 114191253 Glycine, serine, and threonine metabolism
      Thymidylate synthase 114187858 Pyrimidine metabolism
      100 PSU, 500 mg/L 26S proteasome non-ATPase regulatory subunit 3 114189291 Proteosome
      3-isopropylmalate dehydrogenase B 114194981 Valine, leucine, and isoleucine biosynthesis
      Aconitate hydratase, mitochondrial precursor 114194899 Citrate cycle (TCA cycle)
      Branched-chain-amino-acid aminotransferase 114191652 Cysteine and methionine metabolism
      Bystin 114193014 Ribosome biogenesis
      DNA replication licensing factor mcm7 114193195 DNA replication
      Elongation factor G 114188759 Translation
      Elongation factor G 1, mitochondrial precursor 114192760 Translation
      Eukaryotic peptide chain release factor subunit 1 114188901 Translation
      Eukaryotic translation initiation factor 2 gamma subunit 114192814 Translation
      Eukaryotic translation initiation factor 5B 114193915 Translation
      Eukaryotic translation initiation factor 6 114188867 Translation
      Exoglucanase 1 precursor 114192372 Starch and sucrose metabolism
      Glycine cleavage system H protein 114197351 Glycine, serine, and threonine metabolism
      HIRA-interacting protein 5 114193863 Oxidative phosphorylation
      Isovaleryl-CoA dehydrogenase, mitochondrial precursor 114191418 Amino acid metabolism
      Mitochondrial import receptor subunit tom-20 114192401 Transporters
      Multidrug resistance protein 1 114188861 Drug resistance
      Myosin-1 114190321 Cellular processes
      NADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial precursor 114191677 Oxidative phosphorylation
      NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor 114194075 Oxidative phosphorylation
      Nucleolar essential protein 1 114189301 Translation
      Nucleolar protein NOP58 114194165 Translation
      Phenylacrylic acid decarboxylase 114187643 Phenylpropanoid biosynthesis
      Phospho-2-dehydro-3-deoxyheptonate aldolase 114193629 Phenylalanine, tyrosine, and tryptophan biosynthesis
      Prohibitin-2 114188359 Mitochondrial biogenesis
      Queuine tRNA-ribosyltransferase 114187859 queuosine biosynthesis
      Sec14 cytosolic factor 114193260 Transporters
      Small nuclear ribonucleoprotein Sm D1 114192048 Spliceosome
      Thioredoxin reductase 114194755 Response to oxidative stress
      Tyrosyl-tRNA synthetase 114195131 Aminoacyl-tRNA biosynthesis
      Valyl-tRNA synthetase, mitochondrial precursor 114189806 Aminoacyl-tRNA biosynthesis

      Table 2. 

      Unique proteins expressed at varying salinities and Cr (VI) concentrations and combinations by A. terreus.

    • Protein name NCBI gi FCa FCb Protein name NCBI gi FCa FCb
      Commonly upregulated proteins at 0 PSU (17 nos.)
      40S ribosomal protein S5 114197792 2.766 0.738 Hypothetical protein ATEG_07937 114190499 1.383 0.298
      ADP, ATP carrier protein 114194661 1.045 0.756 Hypothetical protein ATEG_08274 114189747 3.400 2.199
      ATP synthase gamma chain, mp 114195813 2.271 3.245 Ketol-acid reductoisomerase, mp 114195083 1.382 0.463
      Bacterial hemoglobin 114195409 0.313 1.337 Mitochondrial phosphate carrier protein 114197783 1.587 2.695
      Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mp 114191205 2.716 1.100 Mitochondrial processing peptidase β subunit 114197569 0.663 1.044
      Hypothetical protein ATEG_04611 114193358 2.318 3.437 S-adenosylmethionine synthetase 114197201 2.128 3.614
      Hypothetical protein ATEG_04814 114193561 0.792 3.772 Sulfate adenylyltransferase 114189197 2.245 1.548
      Hypothetical protein ATEG_06597 114191441 2.031 1.491 Thioredoxin 114190288 1.054 1.366
      Hypothetical protein ATEG_07125 114190809 3.702 4.735
      Commonly downregulated proteins at 0 PSU (28 nos.)
      30 kDa heat shock protein 114195087 −1.489 −3.989 Hypothetical protein ATEG_03766 114193868 −3.495 −4.500
      40S ribosomal protein S7 114193349 −0.400 −1.867 Hypothetical protein ATEG_04029 114194131 −0.329 −5.081
      Adenosylhomocysteinase 114197109 −2.504 −1.255 Hypothetical protein ATEG_07892 114190454 −2.436 −3.554
      Alcohol dehydrogenase I 114188844 −1.262 −2.186 Nucleoside diphosphate kinase 114189539 −0.270 −1.198
      Allergen Asp f 15 precursor 114196299 −1.670 −1.123 Peptidyl-prolyl cis-trans isomerase, mp 114188009 −1.079 −1.164
      ATP-citrate synthase subunit 1 114195637 −0.241 −1.403 Phosphoglycerate kinase 114197170 −0.876 −1.691
      Cell division control protein 3 114191267 −0.026 −1.425 Pyruvate decarboxylase 114193380 −1.080 −1.857
      Citrate synthase, mp 114189463 −1.648 −1.952 Pyruvate kinase 114193787 −1.254 −2.345
      Cytochrome c peroxidase, mp 114194980 −2.517 −2.468 Superoxide dismutase, mp 114197603 −2.990 −5.415
      Enolase 114194476 −0.766 −1.167 Transaldolase 114191388 −0.240 −1.012
      Eukaryotic translation initiation factor 5A 114193909 −1.433 −2.481 Transketolase 1 114197498 −2.501 −3.119
      Fructose-bisphosphate aldolase 114193450 −1.280 −2.084 Triosephosphate isomerase 114192224 −2.191 −2.825
      Glyceraldehyde-3-phosphate dehydrogenase 114188308 −0.692 −1.064 Tubulin beta chain 114197233 −0.815 −2.778
      Histone H2A 114189434 −0.898 −1.043 UDP-glucose 4-epimerase 114190193 −0.734 −2.722
      Commonly upregulated proteins at 35 PSU (63 nos.)
      2,3-bisphosphoglycerate-independent phosphoglycerate mutase 114196604 2.324 3.720 Heat shock 70 kDa protein 114187927 1.578 1.973
      40S ribosomal protein S0 114194180 2.509 3.045 Heat shock protein 82 114189469 4.514 3.642
      40S ribosomal protein S12 114194654 1.124 2.256 Hexokinase 114191625 2.103 1.510
      40S ribosomal protein S4-A 114189168 0.829 1.918 Histone H4.2 114196427 0.609 1.157
      40S ribosomal protein S5 114197792 0.692 2.155 Hypothetical protein ATEG_01302 114196359 0.892 1.508
      40S ribosomal protein S7 114193349 1.349 2.410 Hypothetical protein ATEG_04182 114194284 1.632 2.166
      60S ribosomal protein L13 114196001 0.697 2.429 Hypothetical protein ATEG_05472 114192841 1.102 1.171
      60S ribosomal protein L14-A 114190763 1.619 1.637 Hypothetical protein ATEG_07125 114190809 0.681 1.325
      60S ribosomal protein L17 114197587 0.870 1.694 Hypothetical protein ATEG_07222 114190906 1.819 1.008
      60S ribosomal protein L23A 114188904 0.374 1.561 Inorganic pyrophosphatase 114196689 1.807 1.504
      60S ribosomal protein L4-2 114188716 1.276 3.004 Ketol-acid reductoisomerase, mp 114195083 2.091 2.069
      60S ribosomal protein L43 114187815 1.296 1.853 Malate dehydrogenase, mp 114191202 1.331 0.976
      6-phosphogluconate dehydrogenase 114191912 1.563 2.096 Mitochondrial peroxiredoxin PRX1 114192711 2.872 3.131
      Actin 114190657 1.288 1.599 Mitochondrial phosphate carrier protein 114197783 2.236 2.705
      ADP, ATP carrier protein 114194661 0.997 1.245 Mitochondrial processing peptidase β subunit 114197569 2.160 3.326
      ATP synthase alpha chain, mp 114193514 1.267 1.362 Outer mitochondrial membrane protein porin 114192911 1.732 0.165
      ATP synthase beta chain, mp 114190171 1.010 1.178 Peptidyl-prolyl cis-trans isomerase cyp8 114192233 0.985 1.330
      ATP-citrate synthase subunit 1 114195637 3.057 3.839 Phosphoglycerate kinase 114197170 0.272 1.118
      Bacterial hemoglobin 114195409 2.965 5.151 Predicted protein 114191395 0.951 2.529
      Cell division cycle protein 48 114187782 2.262 1.642 Protein MMF1, mp 114196923 1.349 0.962
      Cerevisin precursor 114191390 1.711 1.105 Rab GDP-dissociation inhibitor 114196519 1.423 1.503
      Conserved hypothetical protein 114196475 1.396 2.587 S-adenosylmethionine synthetase 114197201 2.622 3.822
      Cytochrome c oxidase polypeptide IV, mp 114188084 3.281 3.780 Thioredoxin 114190288 5.011 5.532
      Cytochrome c oxidase polypeptide VI, mp 114188679 1.105 1.648 Transaldolase 114191388 1.929 1.609
      DNA damage checkpoint protein rad24 114188055 1.449 1.457 Transketolase 1 114197498 1.548 0.710
      Elongation factor 1-alpha 114194584 1.020 1.685 Triosephosphate isomerase 114192224 1.975 2.215
      Elongation factor 2 114196384 1.127 1.052 Tubulin beta chain 114197233 1.919 0.493
      Eukaryotic initiation factor 4A 114196711 2.100 1.766 UDP-glucose 4-epimerase 114190193 2.064 1.063
      Fructose-bisphosphate aldolase 114193450 0.739 1.528 Uricase 114196577 1.110 1.717
      Glucose-6-phosphate isomerase 114193156 2.410 3.284 Vacuolar protease A precursor 114193423 1.442 1.539
      Glyceraldehyde-3-phosphate dehydrogenase 114188308 0.718 1.222 Woronin body major protein 114191425 1.183 0.351
      GTP-binding nuclear protein GSP1/Ran 114194939 2.158 2.763
      Commonly downregulated proteins at 35 PSU (02 nos.)
      Catalase B precursor 114190039 −0.738 −1.267 Hypothetical protein ATEG_04940 114192309 −1.152 −3.181
      Hypothetical protein ATEG_02219 114195481 −1.691 −0.240 Hypothetical protein ATEG_07892 114190454 −2.963 −0.709
      Commonly upregulated proteins at 100 PSU (60 nos.)
      40S ribosomal protein S12 114194654 1.270 0.419 ATP synthase D chain, mp 114190764 1.467 1.799
      40S ribosomal protein S14 114196585 1.452 2.090 ATP synthase gamma chain, mp 114195813 1.783 2.225
      40S ribosomal protein S18 114194976 1.482 1.444 ATP synthase subunit 4, mp 114193524 1.860 1.327
      40S ribosomal protein S2 114189125 1.241 1.859 Bacterial hemoglobin 114195409 1.772 2.860
      40S ribosomal protein S22 114192590 2.391 3.118 Cell division cycle protein 48 114187782 0.806 2.239
      40S ribosomal protein S3 114194638 2.251 1.819 Cerevisin precursor 114191390 1.431 0.988
      40S ribosomal protein S4-A 114189168 1.112 2.637 Citrate synthase, mp 114189463 0.473 1.825
      40S ribosomal protein S5 114197792 1.161 1.795 Conserved hypothetical protein 114196475 2.126 2.297
      40S ribosomal protein S6 114194091 2.466 4.689 Cytochrome c 114196337 1.893 1.957
      40S ribosomal protein S7 114193349 1.105 2.259 Cytochrome c oxidase polypeptide IV, mp 114188084 0.740 1.015
      40S ribosomal protein S8-B 114193882 1.527 3.730 D-3-phosphoglycerate dehydrogenase 2 114188915 0.435 2.825
      60S acidic ribosomal protein P0 114195838 1.810 2.371 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mp 114191205 0.997 2.215
      60S ribosomal protein L10-B 114188346 0.697 1.575 Elongation factor 1-alpha 114194584 0.602 1.119
      60S ribosomal protein L11 114192799 1.454 3.276 Glucose-6-phosphate 1-dehydrogenase 114196680 4.509 4.948
      60S ribosomal protein L12 114195804 0.921 1.374 Heat shock protein 60, mp 114188341 1.130 2.925
      60S ribosomal protein L13 114196001 1.628 1.675 Heat shock protein 82 114189469 0.437 1.829
      60S ribosomal protein L14-A 114190763 0.583 1.701 Heat shock protein SSC1, mp 114193179 0.308 1.746
      60S ribosomal protein L17 114197587 3.057 4.125 Hypothetical protein ATEG_03432 114195006 2.416 2.892
      60S ribosomal protein L2 114188833 3.644 3.886 Hypothetical protein ATEG_03766 114193868 0.613 1.904
      60S ribosomal protein L20 114193847 0.326 1.473 Hypothetical protein ATEG_04611 114193358 2.060 1.378
      60S ribosomal protein L22 114194260 1.264 1.760 Hypothetical protein ATEG_08708 114189140 2.900 2.194
      60S ribosomal protein L23 114188046 1.750 2.336 Hypothetical protein ATEG_09084 114188521 0.106 1.874
      60S ribosomal protein L23A 114188904 1.337 2.134 Isocitrate dehydrogenase subunit 2, mp 114197413 2.411 3.027
      60S ribosomal protein L27a 114189407 1.732 3.080 Mitochondrial phosphate carrier protein 114197783 0.882 2.216
      60S ribosomal protein L34-B 114188081 2.250 2.919 Mitochondrial processing peptidase β subunit 114197569 1.436 2.454
      60S ribosomal protein L4-2 114188716 1.634 1.888 NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mp 114191474 0.895 1.475
      60S ribosomal protein L43 114187815 0.561 1.072 Peptidyl-prolyl cis-trans isomerase cyp8 114192233 1.009 0.636
      60S ribosomal protein L7 114195468 1.105 1.453 Pyruvate dehydrogenase E1 component α subunit, mp 114193839 1.026 1.899
      ADP, ATP carrier protein 114194661 0.351 1.904 Thioredoxin 114190288 2.358 1.839
      Aspartate aminotransferase, mp 114197845 0.859 1.208 Tubulin beta chain 114197233 0.194 1.720
      Commonly downregulated proteins at 100 PSU (14 nos.)
      2,3-bisphosphoglycerate-independent phosphoglycerate mutase 114196604 −0.221 −1.250 Hypothetical protein ATEG_07892 114190454 −0.894 −3.342
      Adenosylhomocysteinase 114197109 −1.786 −0.439 Inorganic pyrophosphatase 114196689 −0.643 −2.344
      Aldehyde dehydrogenase 114192389 −1.095 −0.509 Phosphoglycerate kinase 114197170 −0.042 −1.044
      Cytochrome c peroxidase, mp 114194980 −1.986 −1.345 Pyruvate kinase 114193787 −1.707 −1.342
      Fructose-bisphosphate aldolase 114193450 −0.326 −1.110 Superoxide dismutase, mp 114197603 −2.076 −0.414
      Glucose-6-phosphate isomerase 114193156 −1.044 −0.166 Transketolase 1 114197498 −1.322 −0.163
      Hypothetical protein ATEG_03892 114193994 −1.528 −0.492 UTP--glucose-1-phosphate uridylyltransferase 114196870 −0.195 −1.299
      FCa = fold change values for proteins expressed under chromium stress (100 ppm vs. 0 ppm); FCb = fold change values for proteins expressed under chromium stress (500 ppm vs. 0 ppm); mp = mitochondrial precursor.

      Table 3. 

      Protein regulation by A. terreus under chromium stress.