[1]

Touraine P. 2020. Premature ovarian insufficiency: step-by-step genetics bring new insights. Fertility and Sterilit 113:767−68

doi: 10.1016/j.fertnstert.2019.12.032
[2]

Pandey AK, Gupta A, Tiwari M, Prasad S, Pandey AN, et al. 2018. Impact of stress on female reproductive health disorders: Possible beneficial effects of shatavari (Asparagus racemosus). Biomedicine & Pharmacotherapy 103:46−49

doi: 10.1016/j.biopha.2018.04.003
[3]

Li Y, Qiu W, Zhang Z, Han X, Bu G, et al. 2020. Oral oyster polypeptides protect ovary against ᴅ-galactose-induced premature ovarian failure in C57BL/6 mice. Journal of the Science of Food and Agriculture 100:92−101

doi: 10.1002/jsfa.9997
[4]

Liang X, Yan Z, Ma W, Qian Y, Zou X, et al. 2020. Peroxiredoxin 4 protects against ovarian ageing by ameliorating ᴅ-galactose-induced oxidative damage in mice. Cell Death & Disease 11:1053

doi: 10.1038/s41419-020-03253-8
[5]

Allen EG, Charen K, Hipp HS, Shubeck L, Amin A, et al. 2020. Clustering of comorbid conditions among women who carry an FMR1 premutation. Genetics in Medicine 22:758−66

doi: 10.1038/s41436-019-0733-5
[6]

França MM, Mendonca BB. 2020. Genetics of primary ovarian insufficiency in the next-generation sequencing era. Journal of the Endocrine Society 4:bvz037

doi: 10.1210/jendso/bvz037
[7]

Rafique M, AlObaid S, Al-Jaroudi D. 2019. 47, XXX syndrome with infertility, premature ovarian insufficiency, and streak ovaries. Clin Case Rep 7:1238−41

doi: 10.1002/ccr3.2207
[8]

He QD, Guo JJ, Zhang Q, Yau YM, Yu Y, et al. 2022. Effects of Electroacupuncture on the gut microbiome in cisplatin-induced premature ovarian failure mice. Evidence-Based Complementary and Alternative Medicine 2022:9352833

doi: 10.1155/2022/9352833
[9]

Umer A, Khan N, Greene DL, Habiba UE, Shamim S, et al. 2023. The therapeutic potential of human umbilical cord derived mesenchymal stem cells for the treatment of premature ovarian failure. Stem Cell Reviews and Report 19:651−66

doi: 10.1007/s12015-022-10493-y
[10]

Tatone C, Amicarelli F. 2013. The aging ovary − the poor granulosa cells. Fertility and Sterility 99:12−17

doi: 10.1016/j.fertnstert.2012.11.029
[11]

Tamura H, Kawamoto M, Sato S, Tamura I, Maekawa R, et al. 2017. Long-term melatonin treatment delays ovarian aging. Journal of Pineal Research 62:e12381

doi: 10.1111/jpi.12381
[12]

Wu M, Ma L, Xue L, Ye W, Lu Z, et al. 2019. Resveratrol alleviates chemotherapy-induced oogonial stem cell apoptosis and ovarian aging in mice. Aging 11:1030−44

doi: 10.18632/aging.101808
[13]

Yan F, Zhao Q, Gao H, Wang X, Xu K, et al. 2021. Exploring the mechanism of (−)-Epicatechin on premature ovarian insufficiency based on network pharmacology and experimental evaluation. Bioscience Reports 41:BSR20203955

doi: 10.1042/BSR20203955
[14]

Li X, Li X, Deng L. 2022. Chrysin reduces inflammation and oxidative stress and improves ovarian function in D-gal-induced premature ovarian failure. Bioengineered 13:8291−301

doi: 10.1080/21655979.2021.2005991
[15]

Liu YJ, Zhou CY, Qiu CH, Lu XM, Wang YT. 2013. Chlorogenic acid induced apoptosis and inhibition of proliferation in human acute promyelocytic leukemia HL-60 cells. Molecular Medicine Reports 8:1106−10

doi: 10.3892/mmr.2013.1652
[16]

Liang N, Kitts DD. 2015. Role of chlorogenic acids in controlling oxidative and inflammatory stress conditions. Nutrients 8:16

doi: 10.3390/nu8010016
[17]

Tajik N, Tajik M, Mack I, Enck P. 2017. The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: a comprehensive review of the literature. European Journal of Nutrition 56:2215−44

doi: 10.1007/s00394-017-1379-1
[18]

Chen J, Chen D, Yu B, Luo Y, Zheng P, et al. 2022. Chlorogenic acid attenuates oxidative stress-induced intestinal mucosa disruption in weaned pigs. Frontiers in Veterinary Science 9:806253

doi: 10.3389/fvets.2022.806253
[19]

Zheng Y, Li L, Chen B, Fang Y, Lin W, et al. 2022. Chlorogenic acid exerts neuroprotective effect against hypoxia-ischemia brain injury in neonatal rats by activating Sirt1 to regulate the Nrf2-NF-κB signaling pathway. Cell Communication and Signaling 20:84

doi: 10.1186/s12964-022-00860-0
[20]

Zhang SX, Wang DL, Qi JJ, Yang YW, Sun H, et al. 2024. Chlorogenic acid ameliorates the heat stress-induced impairment of porcine Sertoli cells by suppressing oxidative stress and apoptosis. Theriogenology 214:148−56

doi: 10.1016/j.theriogenology.2023.10.018
[21]

Parida S, Sharma D. 2019. The Microbiome-Estrogen Connection and Breast Cancer Risk. Cells 8:1642

doi: 10.3390/cells8121642
[22]

Qi X, Yun C, Pang Y, Qiao J. 2021. The impact of the gut microbiota on the reproductive and metabolic endocrine system. Gut Microbes 13:1894070

doi: 10.1080/19490976.2021.1894070
[23]

Huang F, Cao Y, Liang J, Tang R, Wu S, et al. 2024. The influence of the gut microbiome on ovarian aging. Gut Microbes 16:2295394

doi: 10.1080/19490976.2023.2295394
[24]

Zheng H, Liang X, Zhou H, Zhou T, Liu X, et al. 2023. Integrated gut microbiota and fecal metabolome analyses of the effect of Lycium barbarum polysaccharide on ᴅ-galactose-induced premature ovarian insufficiency. Food & Function 14:7209−21

doi: 10.1039/D3FO01659E
[25]

Yan Z, Dai Y, Fu H, Zheng Y, Bao D, et al. 2018. Curcumin exerts a protective effect against premature ovarian failure in mice. Journal of Molecular Endocrinology 60:261−71

doi: 10.1530/JME-17-0214
[26]

El-Khadragy MF, Al-Megrin WA, Alomar S, Alkhuriji AF, Metwally DM, et al. 2021. Chlorogenic acid abates male reproductive dysfunction in arsenic-exposed mice via attenuation of testicular oxido-inflammatory stress and apoptotic responses. Chemico-Biological Interactions 333:109333

doi: 10.1016/j.cbi.2020.109333
[27]

Bernal AB, Vickers MH, Hampton MB, Poynton RA, Sloboda DM. 2010. Maternal undernutrition significantly impacts ovarian follicle number and increases ovarian oxidative stress in adult rat offspring. PLoS One 5:e15558

doi: 10.1371/journal.pone.0015558
[28]

Liu W, Chen Q, Liu Z, Weng Z, Nguyen TN, et al. 2021. Zihuai recipe alleviates cyclophosphamide-induced diminished ovarian reserve via suppressing PI3K/AKT-mediated apoptosis. Journal of Ethnopharmacology 277:113789

doi: 10.1016/j.jep.2021.113789
[29]

Paulose T, Hannon PR, Peretz J, Craig ZR, Flaws JA. 2012. Estrogen receptor alpha overexpressing mouse antral follicles are sensitive to atresia induced by methoxychlor and its metabolites. Reproductive Toxicology 33:353−60

doi: 10.1016/j.reprotox.2012.01.007
[30]

Bolyen E, Rideout JR, Dillon MR, Bokulich NA, Abnet CC, et al. 2019. Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nature Biotechnology 37:1091

doi: 10.1038/s41587-019-0252-6
[31]

Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJA, et al. 2016. DADA2: high-resolution sample inference from Illumina amplicon data. Nature Methods 13:581−83

doi: 10.1038/nmeth.3869
[32]

McDonald D, Jiang Y, Balaban M, Cantrell K, Zhu Q, et al. 2023. Author Correction: Greengenes2 unifies microbial data in a single reference tree. Nature Biotechnology 42:813

doi: 10.1038/s41587-023-02026-w
[33]

Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, et al. 2011. Metagenomic biomarker discovery and explanation. Genome Biology 12:R60

doi: 10.1186/gb-2011-12-6-r60
[34]

Banerjee S, Chakraborty P, Saha P, Bandyopadhyay SA, Banerjee S, et al. 2012. Ovotoxic effects of galactose involve attenuation of follicle-stimulating hormone bioactivity and up-regulation of granulosa cell p53 expression. PLoS One 7:e30709

doi: 10.1371/journal.pone.0030709
[35]

Wang JL, Liu B, Zhang C, Wang XM, Zhen D, et al. 2019. Effects of icariin on ovarian function in ᴅ-galactose-induced aging mice. Theriogenology 125:157−67

doi: 10.1016/j.theriogenology.2018.10.028
[36]

Hampl R, Šnajderová M, Mardešić T. 2011. Antimüllerian hormone (AMH) not only a marker for prediction of ovarian reserve. Physiological Research 60:217−23

doi: 10.33549/physiolres.932076
[37]

Seifer DB, Baker VL, Leader B. 2011. Age-specific serum anti-Müllerian hormone values for 17,120 women presenting to fertility centers within the United States. Fertility and Sterility 95:747−50

doi: 10.1016/j.fertnstert.2010.10.011
[38]

Atif F, Yousuf S, Stein DG. 2015. Anti-tumor effects of progesterone in human glioblastoma multiforme: role of PI3K/Akt/mTOR signaling. The Journal of Steroid Biochemistry and Molecular Biology 146:62−73

doi: 10.1016/j.jsbmb.2014.04.007
[39]

Wang K, Yang L, Zhou J, Pan X, He Z, et al. 2022. Smilax china L. polysaccharide alleviates oxidative stress and protects from acetaminophen-induced hepatotoxicity via activating the Nrf2-ARE pathway. Frontiers in Pharmacology 13:888560

doi: 10.3389/fphar.2022.888560
[40]

Lynch SV, Pedersen O. 2016. The human intestinal microbiome in health and disease. New England Journal of Medicine 375:2369−79

doi: 10.1056/NEJMra1600266
[41]

Wu J, Zhuo Y, Liu Y, Chen Y, Ning Y, et al. 2021. Association between premature ovarian insufficiency and gut microbiota. BMC Pregnancy and Childbirth 21:418

doi: 10.1186/s12884-021-03855-w
[42]

Ishizuka B. 2021. Current understanding of the etiology, symptomatology, and treatment options in Premature Ovarian Insufficiency (POI). Frontiers in Endocrinology 12:626924

doi: 10.3389/fendo.2021.626924
[43]

Hu S, Ding Q, Zhang W, Kang M, Ma J, et al. 2023. Gut microbial beta-glucuronidase: a vital regulator in female estrogen metabolism. Gut Microbes 15:2236749

doi: 10.1080/19490976.2023.2236749
[44]

Andrani M, Ferrari L, Borghetti P, Cavalli V, De Angelis E, et al. 2024. Short-chain fatty acids modulate the IPEC-J2 cell response to pathogenic E. coli LPS-activated PBMC. Research in Veterinary Science 171:105231

doi: 10.1016/j.rvsc.2024.105231
[45]

Liu X, Mao B, Gu J, Wu J, Cui S, et al. 2021. Blautia - a new functional genus with potential probiotic properties? Gut Microbes 13:1875796

doi: 10.1080/19490976.2021.1875796
[46]

Yan F, Zhao Q, Li Y, Zheng Z, Kong X, et al. 2022. The role of oxidative stress in ovarian aging: a review. Journal of Ovarian Research 15:100

doi: 10.1186/s13048-022-01032-x
[47]

Navarro-Pando JM, Alcocer-Gómez E, Castejón-Vega B, Navarro-Villarán E, Condés-Hervás M, et al. 2021. Inhibition of the NLRP3 inflammasome prevents ovarian aging. Science Advances 7:eabc7409

doi: 10.1126/sciadv.abc7409
[48]

Ayazoglu Demir E, Mentese A, Livaoglu A, Turkmen Alemdar N, Aliyazicioglu Y, et al. 2024. Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats. Drug and Chemical Toxicology 47:213−17

doi: 10.1080/01480545.2023.2172181
[49]

Bacil GP, Romualdo GR, Rodrigues J, Barbisan LF. 2023. Indole-3-carbinol and chlorogenic acid combination modulates gut microbiome and attenuates nonalcoholic steatohepatitis in a murine model. Food Research International 174:113513

doi: 10.1016/j.foodres.2023.113513
[50]

Chen J, Xiao Y, Li D, Zhang S, Wu Y, et al. 2023. New insights into the mechanisms of high-fat diet mediated gut microbiota in chronic diseases. iMeta 2:e69

doi: 10.1002/imt2.69
[51]

Kawano Y, Edwards M, Huang Y, Bilate AM, Araujo LP, et al. 2022. Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome. Cell 185:3501−3019.e20

doi: 10.1016/j.cell.2022.08.005
[52]

Zhang XL, Chen L, Yang J, Zhao SS, Jin S, et al. 2023. Vitamin D alleviates non-alcoholic fatty liver disease via restoring gut microbiota and metabolism. Frontiers in Microbiology 14:1117644

doi: 10.3389/fmicb.2023.1117644
[53]

Sheng J, Yang G, Jin X, Si C, Huang Y, et al. 2022. Corrigendum: Electroacupuncture Combined With Diet Treatment Has a Therapeutic Effect on Perimenopausal Patients With Abdominal Obesity by Improving the Community Structure of Intestinal Flora. Frontiers in Physiology 13:844424

doi: 10.3389/fphys.2022.844424
[54]

Zhao JD, Li Y, Sun M, Yu CJ, Li JY, et al. 2021. Effect of berberine on hyperglycaemia and gut microbiota composition in type 2 diabetic Goto-Kakizaki rats. World Journal of Gastroenterology 27:708−24

doi: 10.3748/wjg.v27.i8.708