[1]

Ke L, Xu W, Gao J, Gao G, Wang H, et al. 2021. Isolation and characterization of thermo-tolerant polyphenol oxidases in a black tea infusion. Food Control 119:107465

doi: 10.1016/j.foodcont.2020.107465
[2]

Xu N, Wei L, Liu J. 2017. Biotechnological advances and perspectives of gamma-aminobutyric acid production. World Journal of Microbiology and Biotechnology 33:64

doi: 10.1007/s11274-017-2234-5
[3]

Liu K, Kim J, Kim DW, Zhang YS, Bao H, et al. 2017. Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep. Nature 548:582−587

doi: 10.1038/nature23663
[4]

Lo H, Lin HH, Chen JK, Situmorang JH, Lai CC. 2018. Involvement of NMDA receptors, nitric oxide, and GABA in rostral ventrolateral medulla in acute ethanol-induced cardiovascular responses in rats. Alcoholism: Clinical and Experimental Research 42:1418−1430

doi: 10.1111/acer.13800
[5]

Zheng S, Zhu J, Li J, Zhang S, Ma Y. 2019. Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels. Frontiers of Agricultural Science and Engineering 6:197−205

doi: 10.15302/J-FASE-2018245
[6]

Du L, Wang C, Li J, Xiao D, Li C, et al. 2013. Optimization of headspace solid-phase microextraction coupled with gas chromatography – mass spectrometry for detecting methoxyphenolic compounds in Pu-erh tea. Journal of Agricultural and Food Chemistry 61:561−568

doi: 10.1021/jf304470k
[7]

Sereshti H, Samadi S, Jalali-Heravi M. 2013. Determination of volatile components of green, black, oolong and white tea by optimized ultrasound-assisted extraction-dispersive liquid–liquid microextraction coupled with gas chromatography. Journal of Chromatography A 1280:1−8

doi: 10.1016/j.chroma.2013.01.029
[8]

Wang H, Hua J, Jiang Y, Yang Y, Wang J, et al. 2020. Influence of fixation methods on the chestnut-like aroma of green tea and dynamics of key aroma substances. Food Research International 136:109479

doi: 10.1016/j.foodres.2020.109479
[9]

Wang ST, Cui WQ, Pan D, Jiang M, Chang B, et al. 2020. Tea polyphenols and their chemopreventive and therapeutic effects on colorectal cancer. World Journal of Gastroenterology 26:562−597

doi: 10.3748/wjg.v26.i6.562
[10]

Yan Z, Zhong Y, Duan Y, Chen Q, Li F. 2020. Antioxidant mechanism of tea polyphenols and its impact on health benefits. Animal Nutrition 6:115−123

doi: 10.1016/j.aninu.2020.01.001
[11]

Donlao N, Ogawa Y. 2019. The influence of processing conditions on catechin, caffeine and chlorophyll contents of green tea (Camelia sinensis) leaves and infusions. LWT 116:108567

doi: 10.1016/j.lwt.2019.108567
[12]

Sonar MP, Rathod VK. 2020. Microwave assisted extraction (MAE) used as a tool for rapid extraction of marmelosin from Aegle marmelos and evaluations of total phenolic and flavonoids content, antioxidant and anti-inflammatory activity. Chemical Data Collections 30:100545

doi: 10.1016/j.cdc.2020.100545
[13]

Ngamkhae N, Monthakantirat O, Chulikhit Y, Boonyarat C, Maneenet J, et al. 2022. Optimization of extraction method for Kleeb Bua Daeng formula and comparison between ultrasound-assisted and microwave-assisted extraction. Journal of Applied Research on Medicinal and Aromatic Plants 28:100369

doi: 10.1016/j.jarmap.2022.100369
[14]

Ye F, Guo X, Li B, Chen H, Qiao X. 2022. Characterization of effects of different tea harvesting seasons on quality components, color and sensory quality of 'yinghong 9' and 'huangyu' large-leaf-variety black tea. Molecules 27:8720

doi: 10.3390/molecules27248720
[15]

Yamanishi T. 1995. VIII. Flavor of tea. Food Reviews International 11:477−525

doi: 10.1080/87559129509541056
[16]

Laddi A, Prakash NR, Kumar A. 2014. Quality evaluation of black CTC teas based upon seasonal variations. International Journal of Food Science & Technology 49:493−500

doi: 10.1111/ijfs.12327
[17]

Dai W, Qi D, Yang T, Lv H, Guo L, et al. 2015. Nontargeted analysis using ultraperformance liquid chromatography–quadrupole time-of-flight mass spectrometry uncovers the effects of harvest season on the metabolites and taste quality of tea (Camellia sinensis L. ). Journal of Agricultural and Food Chemistry 63:9869−9878

doi: 10.1021/acs.jafc.5b03967
[18]

Lv HP, Zhang YJ, Lin Z, Liang YR. 2013. Processing and chemical constituents of Pu-erh tea: a review. Food Research International 53:608−618

doi: 10.1016/j.foodres.2013.02.043
[19]

Ma Y, Ling TJ, Su XQ, Jiang B, Nian B, et al. 2021. Integrated proteomics and metabolomics analysis of tea leaves fermented by Aspergillus niger, Aspergillus tamarii and Aspergillus fumigatus. Food Chemistry 334:127560

doi: 10.1016/j.foodchem.2020.127560
[20]

Mao H, Wang K, Wang Z, Peng J, Ren N. 2020. Metabolic function, trophic mode, organics degradation ability and influence factor of bacterial and fungal communities in chicken manure composting. Bioresour Technol 302:122883

doi: 10.1016/j.biortech.2020.122883
[21]

Xiao Y, Li M, Liu Y, Xu S, Zhong K, et al. 2021. The effect of Eurotium cristatum (MF800948) fermentation on the quality of autumn green tea. Food Chemistry 358:129848

doi: 10.1016/j.foodchem.2021.129848
[22]

Zhang YY, Zhang P, Le MM, Qi Y, Yang Z, et al. 2023. Improving flavor of summer Keemun black tea by solid-state fermentation using Cordyceps militaris revealed by LC/MS-based metabolomics and GC/MS analysis. Food Chemistry 407:135172

doi: 10.1016/j.foodchem.2022.135172
[23]

Yan RH, Lian LF. 1998. Wuxi machinery manufactures ‘Taihu Cuizhu’ tea. Tea 1:52

[24]

Hazafa A, Rehman KU, Jahan N, Jabeen Z. 2020. The role of polyphenol (flavonoids) compounds in the treatment of cancer cells. Nutrition and cancer 72:386−397

doi: 10.1080/01635581.2019.1637006
[25]

Edwards J, Johnson C, Santos-Medellín C, Lurie E, Podishetty NK, et al. 2015. Structure, variation, and assembly of the root-associated microbiomes of rice. Proceedings of the National Academy of Sciences of the United States of America 112:E911−E920

doi: 10.1073/pnas.1414592112
[26]

Bolyen E, Rideout JR, Dillon MR, Bokulich NA, Abnet CC, et al. 2019. Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nature Biotechnology 37:852−857

doi: 10.1038/s41587-019-0209-9
[27]

Magoč T, Salzberg SL. 2011. FLASH: fast length adjustment of short reads to improve genome assemblies. Bioinformatics 27:2957−2963

doi: 10.1093/bioinformatics/btr507
[28]

Zhang J, Feng W, Xiong Z, Dong S, Sheng C, et al. 2024. Investigation of the effect of over-fired drying on the taste and aroma of Lu'an Guapian tea using metabolomics and sensory histology techniques. Food Chemistry 437:137851

doi: 10.1016/j.foodchem.2023.137851
[29]

Kanehisa M, Goto S. 2000. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Research 28:27−30

doi: 10.1093/nar/28.1.27
[30]

Kanehisa M. 2019. Toward understanding the origin and evolution of cellular organisms. Protein Science 28:1947−1951

doi: 10.1002/pro.3715
[31]

Kanehisa M, Furumichi M, Sato Y, Matsuura Y, Ishiguro-Watanabe M. 2025. KEGG: biological systems database as a model of the real world. Nucleic Acids Research 53:D672−D677

doi: 10.1093/nar/gkae909
[32]

Xia W, Li Z, Yu C, Liu Z, Nie J, et al. 2021. Understanding processing, maturity and harvest period effects to authenticate early-spring Longjing tea using stable isotopes and chemometric analyses. Food Control 124:107907

doi: 10.1016/j.foodcont.2021.107907
[33]

Sharma E, Joshi R, Gulati A. 2018. L-Theanine: an astounding sui generis integrant in tea. Food Chemistry 242:601−610

doi: 10.1016/j.foodchem.2017.09.046
[34]

Jia WB, Zhao YQ, Liao SY, Li PW, Zou Y, et al. 2022. Dynamic changes in the diversity and function of bacterial community during black tea processing. Food Research International 161:111856

doi: 10.1016/j.foodres.2022.111856
[35]

Liebelt DJ, Jordan JT, Doherty CJ. 2019. Only a matter of time: the impact of daily and seasonal rhythms on phytochemicals. Phytochemistry Reviews 18:1409−1433

doi: 10.1007/s11101-019-09617-z
[36]

Plugge CM, Zhang W, Scholten JCM, Stams AJM. 2011. Metabolic flexibility of sulfate-reducing bacteria. Frontiers in Microbiology 2:81

doi: 10.3389/fmicb.2011.00081
[37]

Xu J, Wei Y, Li F, Weng X, Wei X. 2022. Regulation of fungal community and the quality formation and safety control of Pu-erh tea. Comprehensive Reviews in Food Science and Food Safety 21:4546−4572

doi: 10.1111/1541-4337.13051
[38]

Ananingsih VK, Sharma A, Zhou W. 2013. Green tea catechins during food processing and storage: a review on stability and detection. Food Research International 50:469−479

doi: 10.1016/j.foodres.2011.03.004
[39]

Abudureheman B, Yu X, Fang D, Zhang H. 2022. Enzymatic oxidation of tea catechins and its mechanism. Molecules 27:942

doi: 10.3390/molecules27030942
[40]

Wang F, Wei Y, Yan T, Wang C, Chao Y, et al. 2022. Sphingomonas sp. Hbc-6 alters physiological metabolism and recruits beneficial rhizosphere bacteria to improve plant growth and drought tolerance. Frontiers in Plant Science 13:1002772

doi: 10.3389/fpls.2022.1002772
[41]

Wang A, Lei Q, Zhang B, Wu J, Fu Z, et al. 2024. Revealing novel insights into the enhancement of quality in black tea processing through microbial intervention. Food Chemistry: X 23:101743

doi: 10.1016/j.fochx.2024.101743
[42]

Nohynek LJ, Suhonen EL, Nurmiaho-Lassila EL, Hantula J, Salkinoja-Salonen M. 1995. Description of four pentachlorophenol-degrading bacterial strains as Sphingomonas chlorophenolica sp. nov. Systematic and Applied Microbiology 18:527−538

doi: 10.1016/S0723-2020(11)80413-3
[43]

Liu L, Shi J, Yuan Y, Yue T. 2022. Changes in the metabolite composition and enzyme activity of fermented tea during processing. Food Research International 158:111428

doi: 10.1016/j.foodres.2022.111428
[44]

Poisson L, Blank I, Dunkel A, Hofmann T. 2017. The chemistry of roasting—decoding flavor formation. In The Craft and Science of Coffee, ed. Folmer B. Amsterdam: Elsevier. pp. 273−309 doi: 10.1016/b978-0-12-803520-7.00012-8

[45]

Wang Q, Yu J, Lin W, Ahammed GJ, Wang W, et al. 2025. L-Theanine metabolism in tea plants: biological functions and stress tolerance mechanisms. Plants 14:492

doi: 10.3390/plants14030492
[46]

Kumar M, Kour D, Yadav AN, Saxena R, Rai PK, et al. 2019. Biodiversity of methylotrophic microbial communities and their potential role in mitigation of abiotic stresses in plants. Biologia 74:287−308

doi: 10.2478/s11756-019-00190-6
[47]

Wang Y, Chen S, Yu O. 2011. Metabolic engineering of flavonoids in plants and microorganisms. Applied Microbiology and Biotechnology 91:949−956

doi: 10.1007/s00253-011-3449-2
[48]

Terahara N. 2015. Flavonoids in foods: a review. Natural Product Communications 10:1934578X1501000334

doi: 10.1177/1934578x1501000334
[49]

Chen L, Zhang S, Feng Y, Jiang Y, Yuan H, et al. 2025. Seasonal variation in non-volatile flavor substances of fresh tea leaves (Camellia sinensis) by integrated lipidomics and metabolomics using UHPLC-Q-Exactive mass spectrometry. Food Chemistry 462:140986

doi: 10.1016/j.foodchem.2024.140986
[50]

Zhang J, Fu X, Dong C, Yu X, Hu R, et al. 2024. Lipidomics reveals the effects of various processing parameters on the lipid composition and activity of roasted coffee oil. LWT 211:116938

doi: 10.1016/j.lwt.2024.116938
[51]

Ali AH, Abdelrahman M, El-Sayed MA. 2019. Alkaloid role in plant defense response to growth and stress. In Bioactive Molecules in Plant Defense, eds. Jogaiah S, Abdelrahman M. Cham: Springer. pp. 145−158 doi: 10.1007/978-3-030-27165-7_9

[52]

D'Amelia V, Aversano R, Chiaiese P, Carputo D. 2018. The antioxidant properties of plant flavonoids: their exploitation by molecular plant breeding. Phytochemistry Reviews 17:611−625

doi: 10.1007/s11101-018-9568-y
[53]

Ye JH, Ye Y, Yin JF, Jin J, Liang YR, et al. 2022. Bitterness and astringency of tea leaves and products: formation mechanism and reducing strategies. Trends in Food Science & Technology 123:130−143

doi: 10.1016/j.jpgs.2022.02.031
[54]

Sanz C, Pérez AG. 2010. Plant metabolic pathways and flavor biosynthesis. In Handbook of Fruit and Vegetable Flavors, ed. Hui YH. Hoboken, New Jersey, USA: Wiley. pp. 129−55 doi: 10.1002/9780470622834.ch9

[55]

Guan Y, Hwarari D, Korboe HM, Ahmad B, Cao Y, et al. 2023. Low temperature stress-induced perception and molecular signaling pathways in plants. Environmental and Experimental Botany 207:105190

doi: 10.1016/j.envexpbot.2022.105190
[56]

Niether W, Smit I, Armengot L, Schneider M, Gerold G, et al. 2017. Environmental growing conditions in five production systems induce stress response and affect chemical composition of cocoa (Theobroma cacao L.) beans. Journal of Agricultural and Food Chemistry 65:10165−10173

doi: 10.1021/acs.jafc.7b04490
[57]

Hodgson JM, Croft KD. 2010. Tea flavonoids and cardiovascular health. Molecular Aspects of Medicine 31:495−502

doi: 10.1016/j.mam.2010.09.004
[58]

Shi J, Yang G, You Q, Sun S, Chen R, et al. 2023. Updates on the chemistry, processing characteristics, and utilization of tea flavonoids in last two decades (2001−2021). Critical Reviews in Food Science and Nutrition 63:4757−4784

doi: 10.1080/10408398.2021.2007353
[59]

Wang LY, Wei K, Jiang YW, Cheng H, Zhou J, et al. 2011. Seasonal climate effects on flavanols and purine alkaloids of tea (Camellia sinensis L.). European Food Research and Technology 233:1049−1055

doi: 10.1007/s00217-011-1588-4
[60]

Shafi U, Mumtaz R, García-Nieto J, Ali Hassan S, Ali Raza Zaidi S, et al. 2019. Precision agriculture techniques and practices: from considerations to applications. Sensors 19:3796

doi: 10.3390/s19173796