[1]

Li Z, Liang Y, Hu H, Shaheen SM, Zhong H, et al. 2021. Speciation, transportation, and pathways of cadmium in soil-rice systems: a review on the environmental implications and remediation approaches for food safety. Environment International 156:106749

doi: 10.1016/j.envint.2021.106749
[2]

Zhao M, Zou G, Li Y, Pan B, Wang X, et al. 2025. Biodegradable microplastics coupled with biochar enhance Cd chelation and reduce Cd accumulation in Chinese cabbage. Biochar 7:31

doi: 10.1007/s42773-024-00418-y
[3]

Zhu L, Tong L, Zhao N, Wang X, Yang X, et al. 2020. Key factors and microscopic mechanisms controlling adsorption of cadmium by surface oxidized and aminated biochars. Journal of Hazardous Materials 382:121002

doi: 10.1016/j.jhazmat.2019.121002
[4]

Zhao FJ, Ma Y, Zhu YG, Tang Z, McGrath SP. 2015. Soil contamination in China: current status and mitigation strategies. Environmental Science & Technology 49:750−759

doi: 10.1021/es5047099
[5]

Feng D, Wang R, Sun X, Liu LN, Liu P, et al. 2023. Heavy metal stress in plants: ways to alleviate with exogenous substances. Science of The Total Environment 897:165397

doi: 10.1016/j.scitotenv.2023.165397
[6]

Azeem I, Wang Q, Adeel M, Shakoor N, Zain M, et al. 2024. Assessing the combined impacts of microplastics and nickel oxide nanomaterials on soybean growth and nitrogen fixation potential. Journal of Hazardous Materials 480:136062

doi: 10.1016/j.jhazmat.2024.136062
[7]

Dissanayake PD, Kim S, Sarkar B, Oleszczuk P, Sang MK, et al. 2022. Effects of microplastics on the terrestrial environment: a critical review. Environmental Research 209:112734

doi: 10.1016/j.envres.2022.112734
[8]

Azeem I, Adeel M, Ahmad MA, Shakoor N, Zain M, et al. 2022. Microplastic and nanoplastic interactions with plant species: trends, meta-analysis, and perspectives. Environmental Science & Technology Letters 9:482−492

doi: 10.1021/acs.estlett.2c00107
[9]

Jiang M, Zhao W, Liang Q, Cai M, Fan X, et al. 2024. Polystyrene microplastics enhanced the toxicity of cadmium to rice seedlings: evidence from rice growth, physiology, and element metabolism. Science of The Total Environment 945:173931

doi: 10.1016/j.scitotenv.2024.173931
[10]

Zhang S, Han B, Sun Y, Wang F. 2020. Microplastics influence the adsorption and desorption characteristics of Cd in an agricultural soil. Journal of Hazardous Materials 388:121775

doi: 10.1016/j.jhazmat.2019.121775
[11]

Zhang Z, Li Y, Qiu T, Duan C, Chen L, et al. 2022. Microplastics addition reduced the toxicity and uptake of cadmium to Brassica chinensis L. Science of The Total Environment 852:158353

doi: 10.1016/j.scitotenv.2022.158353
[12]

Yang R, Cheng L, Li Z, Cui Y, Liu J, et al. 2025. Mechanism of microplastics in the reduction of cadmium toxicity in tomato. Ecotoxicology and Environmental Safety 289:117621

doi: 10.1016/j.ecoenv.2024.117621
[13]

Lian J, Wu J, Zeb A, Zheng S, Ma T, et al. 2020. Do polystyrene nanoplastics affect the toxicity of cadmium to wheat (Triticum aestivum L.)? Environmental Pollution 263:114498

doi: 10.1016/j.envpol.2020.114498
[14]

Imran M, Junaid M, Shafiq S, Liu S, Chen X, et al. 2024. Multiomics analysis reveals a substantial decrease in nanoplastics uptake and associated impacts by nano zinc oxide in fragrant rice (Oryza sativa L.). Journal of Hazardous Materials 474:134640

doi: 10.1016/j.jhazmat.2024.134640
[15]

Li Y, Rahman SU, Qiu Z, Shahzad SM, Nawaz MF, et al. 2023. Toxic effects of cadmium on the physiological and biochemical attributes of plants, and phytoremediation strategies: a review. Environmental Pollution 325:121433

doi: 10.1016/j.envpol.2023.121433
[16]

Yin J, Zhu T, Li X, Yin X, Xu J, et al. 2024. Polystyrene nanoplastics induce cell type-dependent secondary wall reinforcement in rice (Oryza sativa) roots and reduce root hydraulic conductivity. Journal of Hazardous Materials 477:135309

doi: 10.1016/j.jhazmat.2024.135309
[17]

Parrotta L, Guerriero G, Sergeant K, Cai G, Hausman JF. 2015. Target or barrier? The cell wall of early- and later-diverging plants vs cadmium toxicity: differences in the response mechanisms. Frontiers in Plant Science 6:133

doi: 10.3389/fpls.2015.00133
[18]

Qi X, Tam NF, Li WC, Ye Z. 2020. The role of root apoplastic barriers in cadmium translocation and accumulation in cultivars of rice (Oryza sativa L.) with different Cd-accumulating characteristics. Environmental Pollution 264:114736

doi: 10.1016/j.envpol.2020.114736
[19]

Sun XD, Yuan XZ, Jia Y, Feng LJ, Zhu FP, et al. 2020. Differentially charged nanoplastics demonstrate distinct accumulation in Arabidopsis thaliana. Nature Nanotechnology 15:755−760

doi: 10.1038/s41565-020-0707-4
[20]

Wang F, Wang X, Song N. 2021. Polyethylene microplastics increase cadmium uptake in lettuce (Lactuca sativa L.) by altering the soil microenvironment. Science of The Total Environment 784:147133

doi: 10.1016/j.scitotenv.2021.147133
[21]

Zhu Z, Tian H, Tang X, Li J, Zhang Z, et al. 2023. NPs-Ca promotes Cd accumulation and enhances Cd tolerance of rapeseed shoots by affecting Cd transfer and Cd fixation in pectin. Chemosphere 341:140001

doi: 10.1016/j.chemosphere.2023.140001
[22]

Huang F, Hu J, Chen L, Wang Z, Sun S, et al. 2023. Microplastics may increase the environmental risks of Cd via promoting Cd uptake by plants: a meta-analysis. Journal of Hazardous Materials 448:130887

doi: 10.1016/j.jhazmat.2023.130887
[23]

Wang F, Zhang X, Zhang S, Zhang S, Sun Y. 2020. Interactions of microplastics and cadmium on plant growth and arbuscular mycorrhizal fungal communities in an agricultural soil. Chemosphere 254:126791

doi: 10.1016/j.chemosphere.2020.126791
[24]

Azeem I, Adeel M, Ahmad MA, Shakoor N, Jiangcuo GD, et al. 2021. Uptake and accumulation of nano/microplastics in plants: a critical review. Nanomaterials 11:2935

doi: 10.3390/nano11112935
[25]

Hedges LV, Gurevitch J, Curtis PS. 1999. The meta-analysis of response ratios in experimental ecology. Ecology 80:1150−1156

doi: 10.1890/0012-9658(1999)080[1150:TMAORR]2.0.CO;2
[26]

Gurevitch J, Koricheva J, Nakagawa S, Stewart G. 2018. Meta-analysis and the science of research synthesis. Nature 555:175−182

doi: 10.1038/nature25753
[27]

Schwarzer G. 2007. meta: An R package for meta-analysis. R News 7:40−45

[28]

Viechtbauer W, Cheung MWL. 2010. Outlier and influence diagnostics for meta-analysis. Research Synthesis Methods 1:112−125

doi: 10.1002/jrsm.11
[29]

Zhang X, Zhang Y, Li D, Wang J, Ding Y, et al. 2024. Aging properties of polyethylene and polylactic acid microplastics and their adsorption behavior of Cd(II) and Cr(VI) in aquatic environments. Chemosphere 363:142833

doi: 10.1016/j.chemosphere.2024.142833
[30]

Tang S, Yang X, Zhang T, Qin Y, Cao C, et al. 2022. Adsorption mechanisms of metal ions (Pb, Cd, Cu) onto polyamide 6 microplastics: new insight into environmental risks in comparison with natural media in different water matrices. Gondwana Research 110:214−225

doi: 10.1016/j.gr.2022.06.017
[31]

Zong X, Zhang J, Zhu J, Zhang L, Jiang L, et al. 2021. Effects of polystyrene microplastic on uptake and toxicity of copper and cadmium in hydroponic wheat seedlings (Triticum aestivum L.). Ecotoxicology and Environmental Safety 217:112217

doi: 10.1016/j.ecoenv.2021.112217
[32]

Wang B, Wang P, Zhao S, Shi H, Zhu Y, et al. 2023. Combined effects of microplastics and cadmium on the soil-plant system: phytotoxicity, Cd accumulation and microbial activity. Environmental Pollution 333:121960

doi: 10.1016/j.envpol.2023.121960
[33]

Hu T, Chen J. 2022. A review on adsorption and transport of microplastics in soil and the effect of ageing on environmental behavior of pollutants. Rock and Mineral Analysis 41:353−363

doi: 10.15898/j.cnki.11-2131/td.202202180024
[34]

Gao X, Hassan I, Peng Y, Huo S, Ling L. 2021. Behaviors and influencing factors of the heavy metals adsorption onto microplastics: a review. Journal of Cleaner Production 319:128777

doi: 10.1016/j.jclepro.2021.128777
[35]

Hodson ME, Duffus-Hodson CA, Clark A, Prendergast-Miller MT, Thorpe KL. 2017. Plastic bag derived-microplastics as a vector for metal exposure in terrestrial invertebrates. Environmental Science & Technology 51:4714−4721

doi: 10.1021/acs.est.7b00635
[36]

Cao Y, Zhao M, Ma X, Song Y, Zuo S, et al. 2021. A critical review on the interactions of microplastics with heavy metals: mechanism and their combined effect on organisms and humans. Science of The Total Environment 788:147620

doi: 10.1016/j.scitotenv.2021.147620
[37]

Bandow N, Will V, Wachtendorf V, Simon FG. 2017. Contaminant release from aged microplastic. Environmental Chemistry 14:394−405

doi: 10.1071/en17064
[38]

Azeem I, Adeel M, Shakoor N, Zain M, Bibi H, et al. 2024. Co-exposure to tire wear particles and nickel inhibits mung bean yield by reducing nutrient uptake. Environmental Science: Processes & Impacts 26:832−842

doi: 10.1039/d4em00070f
[39]

Rizwan M, Ali S, Zia Ur Rehman M, Rinklebe J, Tsang DCW, et al. 2018. Cadmium phytoremediation potential of Brassica crop species: a review. Science of The Total Environment 631-632:1175−1191

doi: 10.1016/j.scitotenv.2018.03.104
[40]

Huang F, Chen L, Yang X, Jeyakumar P, Wang Z, et al. 2024. Unveiling the impacts of microplastics on cadmium transfer in the soil-plant-human system: a review. Journal of Hazardous Materials 477:135221

doi: 10.1016/j.jhazmat.2024.135221
[41]

Wu X, Yin S, Liu Y, Zhu Y, Jiang T, et al. 2024. Molecular mechanisms and physiological responses of rice leaves co-exposed to submicron-plastics and cadmium: implication for food quality and security. Journal of Hazardous Materials 463:132957

doi: 10.1016/j.jhazmat.2023.132957
[42]

Shakoor N, Hussain M, Adeel M, Azeem I, Ahmad MA, et al. 2023. Lithium-induced alterations in soybean nodulation and nitrogen fixation through multifunctional mechanisms. Science of The Total Environment 904:166438

doi: 10.1016/j.scitotenv.2023.166438
[43]

Chen Z, Feng Y, Guo Z, Han M, Yan X. 2024. Zinc oxide nanoparticles alleviate cadmium toxicity and promote tolerance by modulating programmed cell death in alfalfa (Medicago sativa L.). Journal of Hazardous Materials 469:133917

doi: 10.1016/j.jhazmat.2024.133917
[44]

Fu L, Su T, Wei D, Wu D, Zhang G, et al. 2022. Copper oxide nanoparticles alleviate cadmium toxicity in cereal crops. Environmental Science: Nano 9:3502−3513

doi: 10.1039/d2en00213b
[45]

Zhang X, Zhao Y, Huang L, Luo X, Zhang C, et al. 2025. Zinc oxide nanoparticles alleviated Cd toxicity in Hibiscus syriacus L. by reducing Cd translocation and improving plant growth and root cellular ultrastructure. Journal of Hazardous Materials 491:137920

doi: 10.1016/j.jhazmat.2025.137920
[46]

Sun H, Shao C, Jin Q, Li M, Zhang Z, et al. 2022. Effects of cadmium contamination on bacterial and fungal communities in Panax ginseng-growing soil. BMC Microbiology 22:77

doi: 10.1186/s12866-022-02488-z
[47]

Li Y, Gao Y, Chen W, Zhang W, Lu X. 2024. Shifts in bacterial diversity, interactions and microbial elemental cycling genes under cadmium contamination in paddy soil: implications for altered ecological function. Journal of Hazardous Materials 461:132544

doi: 10.1016/j.jhazmat.2023.132544
[48]

Chen Y, Chen F, Xie M, Jiang Q, Chen W, et al. 2020. The impact of stabilizing amendments on the microbial community and metabolism in cadmium-contaminated paddy soils. Chemical Engineering Journal 395:125132

doi: 10.1016/j.cej.2020.125132
[49]

Li HZ, Zhu D, Lindhardt JH, Lin SM, Ke X, et al. 2021. Long-term fertilization history alters effects of microplastics on soil properties, microbial communities, and functions in diverse farmland ecosystem. Environmental Science & Technology 55:4658−4668

doi: 10.1021/acs.est.0c04849
[50]

Yu H, Liu X, Qiu X, Sun T, Cao J, et al. 2024. Discrepant soil microbial community and C cycling function responses to conventional and biodegradable microplastics. Journal of Hazardous Materials 470:134176

doi: 10.1016/j.jhazmat.2024.134176
[51]

Xiao M, Ding J, Luo Y, Zhang H, Yu Y, et al. 2022. Microplastics shape microbial communities affecting soil organic matter decomposition in paddy soil. Journal of Hazardous Materials 431:128589

doi: 10.1016/j.jhazmat.2022.128589
[52]

Xu L, Yu C, Zhang Q, Yan X, Wei S, et al. 2026. Polylactic acid microplastics inhibit Cd accumulation and growth of Solanum nigrum L.: insights from microbial communities and metabolomic profiles. Environmental Research 288:123194

doi: 10.1016/j.envres.2025.123194
[53]

Li F, Yang X, Zhang Z, Jiang Y, Gong Y. 2024. Behaviour, ecological impacts of microplastics and cadmium on soil systems: a systematic review. Environmental Technology & Innovation 35:103637

doi: 10.1016/j.eti.2024.103637
[54]

Khan Z, Elahi A, Bukhari DA, Rehman A. 2022. Cadmium sources, toxicity, resistance and removal by microorganisms-a potential strategy for cadmium eradication. Journal of Saudi Chemical Society 26:101569

doi: 10.1016/j.jscs.2022.101569
[55]

Backer R, Rokem JS, Ilangumaran G, Lamont J, Praslickova D, et al. 2018. Plant growth-promoting rhizobacteria: context, mechanisms of action, and roadmap to commercialization of biostimulants for sustainable agriculture. Frontiers in Plant Science 9:1473

doi: 10.3389/fpls.2018.01473
[56]

He X, Xu M, Wei Q, Tang M, Guan L, et al. 2020. Promotion of growth and phytoextraction of cadmium and lead in Solanum nigrum L. mediated by plant-growth-promoting rhizobacteria. Ecotoxicology and Environmental Safety 205:111333

doi: 10.1016/j.ecoenv.2020.111333
[57]

Jiang M, Wang B, Ye R, Yu N, Xie Z, et al. 2022. Evidence and impacts of nanoplastic accumulation on crop grains. Advanced Science 9:e2202336

doi: 10.1002/advs.202202336
[58]

Wang Y, Xiang L, Wang F, Wang Z, Bian Y, et al. 2022. Positively charged microplastics induce strong lettuce stress responses from physiological, transcriptomic, and metabolomic perspectives. Environmental Science & Technology 56:16907−16918

doi: 10.1021/acs.est.2c06054
[59]

Kumar R, Ivy N, Bhattacharya S, Dey A, Sharma P. 2022. Coupled effects of microplastics and heavy metals on plants: Uptake, bioaccumulation, and environmental health perspectives. Science of The Total Environment 836:155619

doi: 10.1016/j.scitotenv.2022.155619
[60]

Hussain B, Ashraf MN, Shafeeq-ur-Rahman, Abbas A, Li J, et al. 2021. Cadmium stress in paddy fields: effects of soil conditions and remediation strategies. Science of The Total Environment 754:142188

doi: 10.1016/j.scitotenv.2020.142188
[61]

Pan Y, Bonten LTC, Koopmans GF, Song J, Luo Y, et al. 2016. Solubility of trace metals in two contaminated paddy soils exposed to alternating flooding and drainage. Geoderma 261:59−69

doi: 10.1016/j.geoderma.2015.07.011
[62]

Huang L, Wang Q, Zhou Q, Ma L, Wu Y, et al. 2020. Cadmium uptake from soil and transport by leafy vegetables: a meta-analysis. Environmental Pollution 264:114677

doi: 10.1016/j.envpol.2020.114677
[63]

Tenea AG, Dinu C, Rus PA, Ionescu IA, Gheorghe S, et al. 2024. Exploring adsorption dynamics of heavy metals onto varied commercial microplastic substrates: isothermal models and kinetics analysis. Heliyon 10:e35364

doi: 10.1016/j.heliyon.2024.e35364
[64]

Noor I, Sohail H, Akhtar MT, Cui J, Lu Z, et al. 2024. From stress to resilience: unraveling the molecular mechanisms of cadmium toxicity, detoxification and tolerance in plants. Science of The Total Environment 954:176462

doi: 10.1016/j.scitotenv.2024.176462
[65]

Barbagli A, Jensen BN, Raza M, Schuth C, Rossetto R. 2019. Assessment of soil buffer capacity on nutrients and pharmaceuticals in nature-based solution applications. Environmental Science and Pollution Research 26:759−774

doi: 10.1007/s11356-018-3515-8
[66]

Shakoor N, Adeel M, Ahmad MA, Hussain M, Azeem I, et al. 2023. Environment relevant concentrations of lithium influence soybean development via metabolic reprogramming. Journal of Hazardous Materials 441:129898

doi: 10.1016/j.jhazmat.2022.129898
[67]

Chen Q, Zhao H, Liu Y, Jin L, Peng R. 2023. Factors affecting the adsorption of heavy metals by microplastics and their toxic effects on fish. Toxics 11:490

doi: 10.3390/toxics11060490
[68]

Li Y, Zhang Y, Su F, Wang Y, Peng L, et al. 2022. Adsorption behaviour of microplastics on the heavy metal Cr(VI) before and after ageing. Chemosphere 302:134865

doi: 10.1016/j.chemosphere.2022.134865
[69]

Kapelewska J, Klekotka U, Żadziłko E, Karpińska J. 2021. Simultaneous sorption behaviors of UV filters on the virgin and aged micro-high-density polyethylene under environmental conditions. Science of The Total Environment 789:147979

doi: 10.1016/j.scitotenv.2021.147979
[70]

Ivanic FM, Guggenberger G, Woche SK, Bachmann J, Hoppe M, et al. 2023. Soil organic matter facilitates the transport of microplastic by reducing surface hydrophobicity. Colloids and Surfaces A: Physicochemical and Engineering Aspects 676:132255

doi: 10.1016/j.colsurfa.2023.132255