[1]

Li S, Yu Q, Chen C, Zhang Y, Wu Y, et al. 2019. 中国睡莲属植物育种研究进展 [Breeding Progress of Waterlilies in China]. 植物遗传资源学报 [Journal of Plant Genetic Resources] 20:829−835 (in Chinese)

doi: 10.13430/j.cnki.jpgr.20181209001
[2]

Zhu M, Wang L, Zhang H, Xu Y, Zheng X, et al. 2012. Relationship between the composition of anthocyanins and flower color variation in hardy water lily (Nymphaea spp.) cultivars. Chinese Bulletin of Botany 47:437−453

doi: 10.3724/sp.j.1259.2012.00437
[3]

Zhu M. 2018. The flavonoid composition and coloration mechanism in water lily petals. Thesis. Nanjing Agricultural University, China. 144 pp
[4]

Cao J, Li F, Sun C. 2025. 睡莲属植物的研究进展 [Research Progress on Nymphaea]. 植物遗传资源学报 [Journal of Plant Genetic Resources] 26:207−217 (in Chinese)

doi: 10.13430/j.cnki.jpgr.20240524001
[5]

Yu C. 2019. 热带睡莲胆碱氧化酶基因CodA的转化及其耐寒生理研究 [Studies on transformation of the choline oxidase gene CodA and physiological mechanism in tropical waterlily]. Thesis. Zhejiang University, China. 87 pp (in Chinese)
[6]

Xu M, Chen F, Qi S, Zhang L, Wu S. 2018. Loss or duplication of key regulatory genes coincides with environmental adaptation of the stomatal complex in Nymphaea colorata and Kalanchoe laxiflora. Horticulture Research 5:42

doi: 10.1038/s41438-018-0048-8
[7]

Bonilla-Barbosa J, Novelo A, Hornelas Orozco Y, Márquez-Guzmán J. 2000. Comparative seed morphology of Mexican Nymphaea species. Aquatic Botany 68:189−204

doi: 10.1016/S0304-3770(00)00125-X
[8]

Zhou X. 2013. 萍蓬草的化学成分研究 [Studies on chemical constituents from Nuphar pumilum (Hoffm.) DC]. Thesis. Southwest Jiaotong University, China. 64 pp (in Chinese)
[9]

Gao Z. 2020. 芡实 [Semen Euryales]. 中国食品药品监管 [China Food & Drug Administration Magazine]. 107 pp (in Chinese)
[10]

Zhou Q, Fu D, Jin X. 2006. 克鲁兹王莲(睡莲科)的开花生物学研究 [Floral biology of Victoria cruziana (Nymphaeaceae)]. 西北植物学报 [Acta Botanica Boreali-Occidentalia Sinica] 26(8):1526−1533 (in Chinese)

doi: 10.3321/j.issn:1000-4025.2006.08.002
[11]

Zhu H, Du J, Liu Z, Sun Y, Li M, et al. 2020. 我国野生莼菜考察及遗传多样性研究 [Investigation and genetic diversity of wild water shield (Brasenia schreberi) in China]. 植物遗传资源学报 [Journal of Plant Genetic Resources] 21:1586−1595 (in Chinese)

doi: 10.13430/j.cnki.jpgr.20200529001
[12]

Liu H, Huang W, Huang L, Xiong H, Wu Z, et al. 2019. 莼菜资源及其营养成份研究进展 [Research progress on resources and nutritional components of Brasenia schreberi]. 植物学研究 [Botanical Research] 8:7−14 (in Chinese)

doi: 10.12677/BR.2019.81002
[13]

Fan J, Li H, Yang Z, Zhu G. 2019. 基于本土最优模型模拟入侵物种水盾草在中国的潜在分布 [Selecting the best native individual model to predict potential distribution of Cabomba caroliniana in China]. 生物多样性 [Biodiversity Science] 27:140−148 (in Chinese)

doi: 10.17520/biods.2018232
[14]

Iles WJD, Lee C, Sokoloff DD, Remizowa MV, Yadav SR, et al. 2014. Reconstructing the age and historical biogeography of the ancient flowering-plant family Hydatellaceae (Nymphaeales). BMC Evolutionary Biology 14:102

doi: 10.1186/1471-2148-14-102
[15]

Zhao J, Xu F, Ji T, Gu Z, Li C. 2014. 睡莲属植物化学成分及生物活性研究进展 [Advances in the study on chemical constituents and biological activities in Nymphaea genus]. 天然产物研究与开发 [Nat Prod Res Dev] 26:142−147,141 (in Chinese)

doi: 10.16333/j.1001-6880.2014.01.027
[16]

Li Q, Maiwulajiang A, Xu F, Song M, Zhao J, et al. 2016. 老鹳草素药理研究进展 [Research progress in pharmaceutical activities of Geraniin]. 中国中医药信息杂志 [Chinese Journal of Information on TCM] 23:125−128 (in Chinese)

doi: 10.3969/j.issn.1005-5304.2016.08.034
[17]

Elegami AA, Bates C, Gray AI, MacKay SP, Skellern GG, et al. 2003. Two very unusual macrocyclic flavonoids from the water lily Nymphaea lotus. Phytochemistry 63:727−731

doi: 10.1016/S0031-9422(03)00238-3
[18]

Liu RN, Wang W, Ding Y, Xie WD, Ma C, et al. 2007. A new flavonol glycoside and activity of compounds from the flower of Nymphaea candida. Journal of Asian Natural Products Research 9:333−338

doi: 10.1080/10286020600727665
[19]

Yu F, Xu S, Zhang Z, Chen L, Zeng Y, et al. 2021. 香水莲花化学成分和药理活性研究进展 [Advances in study on chemical constituents and pharmacological activities of Nymphaea hybrida peck]. 食品与生物技术学报 [Journal of Food Science and Biotechnology] 40:18−24 (in Chinese)

doi: 10.3969/j.issn.1673-1689.2021.06.003
[20]

Zhu M, Zheng X, Shu Q, Li H, Zhong P, et al. 2012. Relationship between the composition of flavonoids and flower colors variation in tropical water lily (Nymphaea) cultivars. PLoS One 7:e34335

doi: 10.1371/journal.pone.0034335
[21]

Panklai T, Suphrom N, Temkitthawon P, Totoson P, Chootip K, et al. 2023. Phosphodiesterase 5 and arginase inhibitory activities of the extracts from some members of Nelumbonaceae and Nymphaeaceae families. Molecules 28:5821

doi: 10.3390/molecules28155821
[22]

Zhao J, Liu T, Ma L, Yan M, Gu Z, et al. 2011. Antioxidant and preventive effects of extract from Nymphaea candida flower on in vitro immunological liver injury of rat primary hepatocyte cultures. Evidence-Based Complementary and Alternative Medicine 2011:497673

doi: 10.1093/ecam/nep003
[23]

Alam M, Ju MK, Lee SH. 2017. DNA protecting activities of Nymphaea nouchali (Burm. f) flower extract attenuate t-BHP-induced oxidative stress cell death through Nrf2-mediated induction of heme Oxygenase-1 expression by activating MAP-kinases. International Journal of Molecular Sciences 18:2069

doi: 10.3390/ijms18102069
[24]

Acharya J, Dutta M, Chaudhury K, De B. 2018. Metabolomics and chemometric study for identification of acetylcholinesterase inhibitor(s) from the flower extracts of Nymphaea pubescens. Journal of Food Biochemistry 42:e12575

doi: 10.1111/jfbc.12575
[25]

Zhao J, Xu F, Ji T, Chem Y, Li C, Tan W. 2013. 雪白睡莲花酚类成分研究 [Studies on phenolic compounds from buds of Nymphaea candida Presl]. 天然产物研究与开发 [Natural Product Research and Development] 25:916−918

doi: 10.3969/j.issn.1001-6880.2013.07.010
[26]

Cudalbeanu M, Ghinea IO, Furdui B, Dah-Nouvlessounon D, Raclea R, et al. 2018. Exploring new antioxidant and mineral compounds from Nymphaea alba wild-grown in Danube Delta biosphere. Molecules 23:1247

doi: 10.3390/molecules23061247
[27]

Naznin M, Alam MB, Lee SH, Kim S. 2024. Optimizing ultrasonic-assisted extraction and untargeted metabolite identification from red water lily (nymphaea rubra) leaves with enhanced antioxidant activity. Food Chemistry Advances 4:100696

doi: 10.1016/j.focha.2024.100696
[28]

Vahekeni N, Brillatz T, Rahmaty M, Cal M, Keller-Maerki S, et al. 2024. Antiprotozoal activity of plants used in the management of sleeping sickness in Angola and bioactivity-guided fractionation of Brasenia schreberi J.F. Gmel and Nymphaea lotus L. active against T. b. rhodesiense. Molecules 29:1611

doi: 10.3390/molecules29071611
[29]

Zhang Z, ElSohly HN, Li XC, Khan SI, Broedel SE, et al. 2003. Phenolic compounds from Nymphaea odorata. Journal of Natural Products 66:548−550

doi: 10.1021/np020442j
[30]

Cheng Y, Ma G, Zhao Y, Sheng Y, Li X, et al. 2019. 睡莲花露主要成分及抗氧化作用 [The main metabolites and antioxidation effect of waterlily stigmatic exudate]. 食品研究与开发 [Food Research and Development] 40:108−114 (in Chinese)

doi: 10.3969/j.issn.1005-6521.2019.08.019
[31]

Xu H, Zhang W, Jiang H, Jin J, Shan C, et al. 2008. 香水莲花挥发油的气相色谱-质谱分析 [Analysis of essential oil from the flowers of Nymphaea hybrida by GC-MS]. 食品研究与开发 [Food Research and Development] 29(9):101−103 (in Chinese)

doi: 10.3969/j.issn.1005-6521.2008.09.030
[32]

Zhou Q, Zeng Y, Shan J, Zhu Z. 2019. Study of volatiles from flowers of Nymphaea hybrida by HS-SPME-GC-MS. Chemistry of Natural Compounds 55:951−952

doi: 10.1007/s10600-019-02857-7
[33]

Ishrat N, Gupta A, Khan MF, Shahab U, Khan MS, et al. 2024. Phytoconstituents of Nymphaea rubra flowers and their anti-diabetic metabolic targets. Fitoterapia 176:106014

doi: 10.1016/j.fitote.2024.106014
[34]

Su Q, Tian M, Wang H, Wang L, Liu J, et al. 2022. 睡莲属 62 个栽培种花朵挥发性成分GC-MS分析热带睡莲和寒带睡莲花香化合物存在差异 [Volatile components in flowers of 62 Nymphaea cultivars by GC-MS]. 热带亚热带植物学报 [Journal of Tropical and Subtropical Botany] 30:567−574 (in Chinese)

doi: 10.11926/jtsb.4498
[35]

Zhou Q, Zhao F, Shi M, Zhang H, Zhu Z. 2024. Variation in the floral scent chemistry of Nymphaea 'Eldorado', a valuable water lily, with different flowering stages and flower parts. Plants 13:939

doi: 10.3390/plants13070939
[36]

Legault J, Perron T, Mshvildadze V, Girard-Lalancette K, Perron S, et al. 2011. Antioxidant and anti-inflammatory activities of quercetin 7-O-β-D-glucopyranoside from the leaves of Brasenia schreberi. Journal of Medicinal Food 14:1127−1134

doi: 10.1089/jmf.2010.0198
[37]

Han F, Li J, Yuan J, Yu J. 2021. 四大产区莼菜黄酮类物质组成分析及抗氧化、抑菌活性研究 [Composition analysis and antioxidant and antibacterial activities of flavonoids of Brasenia schreberi in four main areas]. 食品与发酵工业 [Food and Fermentation Industries] 47:236−242 (in Chinese)

doi: 10.13995/j.cnki.11-1802/ts.024509
[38]

Shimoda H. 2014. Anti-adipogenic polyphenols of water shield suppress TNF-α-induced cell damage and enhance expression of HAS2 and HAPB2 in adiponectin- treated dermal fibroblasts. Natural Products Chemistry & Research 2(5):146

doi: 10.4172/2329-6836.1000146
[39]

Xu Z, Da X, Qu J, Luo B, Lin Q. 2025. Optimization of synchronous extraction of polysaccharides and polyphenols from Brasenia schreberi via ultrasonic-assisted aqueous two-phase system: modeling, structural characterization, and antioxidant properties. LWT 232:118403

doi: 10.1016/j.lwt.2025.118403
[40]

Zhou X, Zhang J, Huang S, Zhou X. 2013. 萍蓬草属植物中生物碱成分和药理作用研究进展 [Research progress in alkaloids in plants of Nuphar Smith and their pharmacological effects]. 中草药 [Chinese Traditional and Herbal Drugs] 44:910−917 (in Chinese)
[41]

Miyazawa M, Yoshio K, Ishikawa Y, Kameoka H. 1998. Insecticidal alkaloids against Drosophila melanogaster from Nuphar japonicum DC. Journal of Agricultural and Food Chemistry 46:1059−1063

doi: 10.1021/jf9701547
[42]

Peng K, Zhou X, A P, Zhou X. 2014. 萍蓬草挥发油化学成分研究 [Chemical constituents of the essential oil from Nuphar pumilum (Hoffm.) DC]. 时珍国医国药[Lishizhen Medicine and Materia Medica Research] 25:1312−1313 (in Chinese)

doi: 10.3969/j.issn.1008-0805.2014.06.012
[43]

Orejola JJ, Era M, Matsuo Y, Saito Y, Tanaka T. 2020. Nupharanin, the first ellagitannin with 1, 4-dehydrohexahydroxydiphenoyl-α-d-glucopyranose from Nuphar japonicum. Tetrahedron 76:131204

doi: 10.1016/j.tet.2020.131204
[44]

Lin C, Li L, Liu S, Chen S, Yin L, et al. 2024. Functionalized magnetic particles coupled with LC-MS strategy facilitated discovery of trace thioalkaloids with potent immunosuppressive activity. Bioorganic Chemistry 149:107529

doi: 10.1016/j.bioorg.2024.107529
[45]

Zhang L, Chen F, Zhang X, Li Z, Zhao Y, et al. 2020. The water lily genome and the early evolution of flowering plants. Nature 577:79−84

doi: 10.1038/s41586-019-1852-5
[46]

Zhou Q, Shi M, Zhang H, Zhu Z. 2022. Comparative study of the petal structure and fragrance components of the Nymphaea hybrid, a precious water lily. Molecules 27:408

doi: 10.3390/molecules27020408
[47]

Jiang Y, Liu G, Zhang W, Zhang C, Chen X, et al. 2021. Biosynthesis and emission of methyl hexanoate, the major constituent of floral scent of a night-blooming water lily Victoria cruziana. Phytochemistry 191:112899

doi: 10.1016/j.phytochem.2021.112899
[48]

Sun Y, Qi Z, Xu Y, Li C, Zhao J, et al. 2024. Anti-inflammatory, analgesic, antitussive and antipyretic activities of polyphenol-enriched fraction from Nymphaea candida. Journal of Ethnopharmacology 324:117789

doi: 10.1016/j.jep.2024.117789
[49]

Li J, Wang H, AliTursun M, Li L, Liu N, et al. 2012. 四种维药对常见呼吸道病毒作用的体外实验研究 [Abstract of the study on four Uygur medicines' effect on common viruses associated with respiratory infections in vitro]. 中国民族医药杂志 [Journal of Chinese Ethnomedicine] 18:38−40 (in Chinese)

doi: 10.3969/j.issn.1006-6810.2012.09.025
[50]

Chen Q, Shen Q, Chen L, Bai J, Chu Z, et al. 2020. 莼菜水馒头制作配方的优化 [Formulation optimization of the gel food with Brasenia schreberi]. 食品工业科技 [Science and Technology of Food Industry] 41:162−168,174 (in Chinese)

doi: 10.13386/j.issn1002-0306.2020010262
[51]

Li Q, Li C, Zhan Y, Abudureyimu M, Xu F, et al. 2017. 睡莲花提取物对酪氨酸酶的抑制作用及其动力学研究 [Inhibitory action of extracts from water lily flower on tyrosinase activity and its kinetics]. 日用化学工业 [China Surfactant Detergent & Cosmetics] 47:219−222 (in Chinese)

doi: 10.13218/j.cnki.csdc.2017.04.008
[52]

Mo X, Li A, Yu Q, Zhang J, Huang Z, et al. 2019. 睡莲花多糖的超声波提取工艺及其抗氧化活性研究 [Ultrasound extraction technology and antioxidant activity of polysaccharides from waterlily flower]. 粮食科技与经济 [Grain Deep Processing and Food] 44:91−94 (in Chinese)

doi: 10.16465/j.gste.cn431252ts.20190421
[53]

Rehman S, Ali Ashfaq U, Ijaz B, Riazuddin S. 2018. Anti-hepatitis C virus activity and synergistic effect of Nymphaea alba extracts and bioactive constituents in liver infected cells. Microbial Pathogenesis 121:198−209

doi: 10.1016/j.micpath.2018.05.023
[54]

Cudalbeanu M, Furdui B, Cârâc G, Barbu V, Iancu AV, et al. 2020. Antifungal, antitumoral and antioxidant potential of the Danube Delta Nymphaea alba extracts. Antibiotics 9:7

doi: 10.3390/antibiotics9010007
[55]

Al-Harbi LN, Subash-Babu P, Binobead MA, Alhussain MH, AlSedairy SA, et al. 2020. Potential metabolite nymphayol isolated from water lily (Nymphaea stellata) flower inhibits MCF-7 human breast cancer cell growth via upregulation of Cdkn2a, pRb2, p53 and downregulation of PCNA mRNA expressions. Metabolites 10:280

doi: 10.3390/metabo10070280
[56]

N'Guessan BB, Asiamah AD, Arthur NK, Frimpong-Manso S, Amoateng P, et al. 2021. Ethanolic extract of Nymphaea lotus L. (Nymphaeaceae) leaves exhibits in vitro antioxidant, in vivo anti-inflammatory and cytotoxic activities on Jurkat and MCF-7 cancer cell lines. BMC Complementary Medicine and Therapies 21:22

doi: 10.1186/s12906-020-03195-w
[57]

Chatterjee D, Singh B, Paira K, Das S. 2024. The apoptotic property of Nymphaea caerulea flower extract on acute myeloid leukaemia cell line, THP-1. Asian Pacific Journal of Cancer Prevention 25:123−137

doi: 10.31557/apjcp.2024.25.1.123
[58]

Anand A, Komati A, Katragunta K, Shaik H, Nagendla NK, et al. 2021. Phytometabolomic analysis of boiled rhizome of Nymphaea nouchali (Burm. f.) using UPLC-Q-TOF-MSE, LC-QqQ-MS & GC–MS and evaluation of antihyperglycemic and antioxidant activities. Food Chemistry 342:128313

doi: 10.1016/j.foodchem.2020.128313
[59]

Xiao S, Xu Y, Wang K, He C, Geng J, et al. 2025. 睡莲属植物化学成分及药理作用研究进展 [Research progress on chemical compounds and pharmacological actions in Nymphaea genus]. 新疆大学学报(自然科学版中英文) [Journal of Xinjiang University (Natural Science Edition in Chinese and English)] 42:82−98 (in Chinese)

doi: 10.13568/j.cnki.651094.651316.2023.12.04.0001
[60]

Fan Y, Wang J, Yu W, Ji H, Lu W, et al. 2018. 同时蒸馏萃取制备延药睡莲精油及其抗氧化研究 [Preparation of essential oil from Nymphaea stellata by the method of simultaneous distillation extraction and its antioxidative activities]. 食品研究与开发 [Food Research and Development] 39:19−23 (in Chinese)

doi: 10.3969/j.issn.1005-6521.2018.12.005
[61]

Cong H, Hu G, Wang W, Xie X, Yao L, Lu J. 2018. 香水莲花多糖粗提物的除蛋白及抗氧化活性研究 [Study on protein removal and antioxidant activity of crude polysaccharide from Nymphaea hybrid]. 上海交通大学学报 (农业科学版) [Journal of Shanghai Jiaotong University (Agricultural Science)] 36:45−49 (in Chinese)

doi: 10.3969/J.ISSN.1671-9964.2018.06.008
[62]

Gueye FK, Niang L, Dieng B, Gueye MF, Ayessou NC, et al. 2022. Phytochemical screening and antioxidant activities of water lilies seeds, neglected and underused species in the delta and lower valley of the Senegal River. American Journal of Plant Sciences 13:756−765

doi: 10.4236/ajps.2022.136051
[63]

Ishola IO, Akinleye MO, Afolayan OO, Okonkwo HE, Animashaun OT, et al. 2022. Anticonvulsant activity of Nymphaea lotus Linn. extract in mice: the role of GABAergic-glutamatergic neurotransmission and antioxidant defence mechanisms. Epilepsy Research 181:106871

doi: 10.1016/j.eplepsyres.2022.106871
[64]

Bhandarkar MR, Khan A. 2004. Antihepatotoxic effect of Nymphaea stellata Willd., against carbon tetrachloride-induced hepatic damage in albino rats. Journal of Ethnopharmacology 91:61−64

doi: 10.1016/j.jep.2003.11.020
[65]

Debnath S, Ghosh S, Hazra B. 2013. Inhibitory effect of Nymphaea pubescens Willd. flower extract on carrageenan-induced inflammation and CCl4-induced hepatotoxicity in rats. Food and Chemical Toxicology 59:485−491

doi: 10.1016/j.fct.2013.06.036
[66]

Jiang H, Jin J, Zhao B, Zhang W. 2012. 香水莲花总提取物对小鼠急性酒精肝损伤的实验研究 [Study on protective effects of Nymphaea hybrid on acute alcohol liver injury in mice]. 中国野生植物资源 [Chinese Wild Plant Resources] 31:18−19,26 (in Chinese)
[67]

Nasiruddin M, Khan IA, Arif SH. 2019. Ameliorative potentials of Nymphaea alba on hepatotoxicity and oxidative damage induced by chronic exposure to isoniazid in rats. International Research Journal of Pharmacy 10:60−64

doi: 10.7897/2230-8407.1007219
[68]

Zhao J, Tuersunmaimaiti M, Ji T, Liu T, Xu F. 2021. Hepatoprotective activity of isostrictiniin from Nymphaea candida on Con A-induced acute liver injury in mice. Natural Product Research 35:1662−1666

doi: 10.1080/14786419.2019.1622105
[69]

Ma J, Zhang S, Lü M, Wang H, Chen X, et al. 2017. Protective effect of nicotiflorin from Nymphaea candida on D-Galinduced acute liver injury in mice. Carcinogenesis, Teratogenesis & Mutagenesis 29:370−373,378

doi: 10.3969/j.issn.1004-616x.2017.05.009
[70]

Oyeyemi IT, Akanni OO, Adaramoye OA, Bakare AA. 2017. Methanol extract of Nymphaea lotus ameliorates carbon tetrachloride-induced chronic liver injury in rats via inhibition of oxidative stress. Journal of Basic and Clinical Physiology and Pharmacology 28:43−50

doi: 10.1515/jbcpp-2016-0029
[71]

Oyeyemi IT, Adesina IA, Sulaiman KA, Ajayi IT, Nabofa EEW. 2024. Ethanol extract of Nymphaea lotus Linn. inhibited hepatic fibrogenesis in carbon tetrachloride-intoxicated Wistar rats. Clinical Phytoscience 10:22

doi: 10.1186/s40816-024-00384-9
[72]

Xu R, Cao X, Wang M, Liu W, Ma W. 2009. 睡莲叶黄酮的提取及其抑菌活性研究 [Studies on the extracting technology of flavones from Pygmy Waterlily leaves and their antibacterial activity]. 食品科技 [Food Science and Technology] 34:190−192,197 (in Chinese)
[73]

Dash BK, Sen MK, Alam K, Hossain K, Islam R, et al. 2013. Antibacterial activity of Nymphaea nouchali (Burm. f) flower. Annals of Clinical Microbiology and Antimicrobials 12:27

doi: 10.1186/1476-0711-12-27
[74]

Liu D, Luo J, Xiang W, Kuang L, Sai Fuding A, et al. 2021. 雪白睡莲花粗提物对奶牛乳房炎主要致病菌体外抑菌和抗炎作用 [Antimicrobial and anti-inflammatory effects of crude extract of Nymphaea candida on major pathogens in cow mastitis in vitro]. 动物医学进展 [Progressin Veterinary Medicine] 42:17−21 (in Chinese)

doi: 10.3969/j.issn.1007-5038.2021.07.004
[75]

Parimala M, Shoba FG. 2014. In vitro antimicrobial activity and HPTLC analysis of hydroalcoholic seed extract of Nymphaea nouchali Burm. f. BMC Complementary and Alternative Medicine 14:361

doi: 10.1186/1472-6882-14-361
[76]

Hossain MA, Lee SJ, Park JY, Reza MA, Kim TH, et al. 2015. Modulation of quorum sensing-controlled virulence factors by Nymphaea tetragona (water lily) extract. Journal of Ethnopharmacology 174:482−491

doi: 10.1016/j.jep.2015.08.049
[77]

Batool R, Kalsoom A, Akbar I, Arshad N, Jamil N. 2018. Antilisterial Effect of Rosa damascena and Nymphaea alba in Mus musculus. BioMed Research International 2018:4543723

doi: 10.1155/2018/4543723
[78]

Hsu CL, Fang SC, Yen GC. 2013. Anti-inflammatory effects of phenolic compounds isolated from the flowers of Nymphaea mexicana Zucc. Food & Function 4:1216−1222

doi: 10.1039/c3fo60041f
[79]

Zhang Z, Jiang S, Tian H, Zeng Y, He K, et al. 2021. Ethyl acetate fraction from Nymphaea hybrida Peck modulates inflammatory responses in LPS-stimulated RAW 264.7 cells and acute inflammation murine models. Journal of Ethnopharmacology 269:113698

doi: 10.1016/j.jep.2020.113698
[80]

Rege MG, Ayanwuyi LO, Zezi AU, Odoma S. 2021. Anti-nociceptive, anti-inflammatory and possible mechanism of anti-nociceptive action of methanol leaf extract of Nymphaea lotus Linn (Nymphaeceae). Journal of Traditional and Complementary Medicine 11:123−129

doi: 10.1016/j.jtcme.2020.02.010
[81]

Rajagopal K, Sasikala K, Ragavan B. 2008. Hypoglycemic and antihyperglycemic activity of Nymphaea stellata flowers in normal and alloxan diabetic rats. Pharmaceutical Biology 46:654−659

doi: 10.1080/13880200802182554
[82]

Zhang W, Jiang H, Xu H, Liu X, Zhang J. 2009. 香水莲花降血脂作用的实验研究 [Experimental study on reducing blood lipid of Nymphaea hybrid]. 食品工业科技 [Science and Technology of Food Industry] 111−112,116 (in Chinese)
[83]

Zhang D, Yao Z, Hou B, Zhang W, Sun L. 2017. 香水莲花提取物对胰脂肪酶活性的抑制作用 [Inhibitory effect of extracts from Nymphaea hybrid flowers on pancreatic lipase]. 食品科技 [Food Science and Technology] 42:227−231 (in Chinese)
[84]

Liu R, Wang W, Xie W, Ding Y, Du L. 2006. 雪白睡莲花中黄酮类成分抗氧化及拟缺血对神经细胞作用的研究 [Nymphaea candida flavonols: antioxidation and ischemic injury effect on neurons]. 世界科学技术-中医药现代化 [World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica] 33−36,29 (in Chinese)

doi: 10.3969/j.issn.1674-3849.2006.05.007
[85]

Wang W, Ye Q, Xiang T, Wu X, Shen J. 2019. 香水莲花提取物对东莨菪碱诱导记忆障碍小鼠学习记忆能力的影响 [Effect of Nymphaea hybrid extract on learning and memory ability of scopolamine-induced memory impaired mice]. 天然产物研究与开发 [Natural Product Research and Development] 31:299−305 (in Chinese)

doi: 10.16333/j.1001-6880.2019.2.019
[86]

Hong H, Gao M, Zhou M, Wang A, Hua R, et al. 2024. Ethyl acetate extract of Nymphaea candida Presl: a potential anti-depressant and neuroprotective treatment strategy. Biomedicine & Pharmacotherapy 179:117304

doi: 10.1016/j.biopha.2024.117304
[87]

Kameni PM, Dzeufiet DPD, Bilanda DC, Mballa MF, Mengue NYS, et al. 2019. Nymphaea lotus Linn. (Nymphaeaceae) alleviates sexual disability in L-NAME hypertensive male rats. Evidence-Based Complementary and Alternative Medicine 2019:8619283

doi: 10.1155/2019/8619283
[88]

Alam MB, Ahmed A, Motin MA, Kim S, Lee SH. 2018. Attenuation of melanogenesis by Nymphaea nouchali (Burm. f) flower extract through the regulation of cAMP/CREB/MAPKs/MITF and proteasomal degradation of tyrosinase. Scientific Reports 8:13928

doi: 10.1038/s41598-018-32303-7
[89]

Park G, Sim Y, Lee W, Sung SH, Oh MS. 2016. Protection on skin aging mediated by antiapoptosis effects of the water lily (Nymphaea tetragona Georgi) via reactive oxygen species scavenging in human epidermal keratinocytes. Pharmacology 97:282−293

doi: 10.1159/000444022
[90]

Tang X, Feng Q, Liu D, Lv Z, Hong M. 2020. Evaluation of antioxidative and moisturizing effects of lotus extracts. Daily Chemical Science 43:52−56
[91]

Zhuang Z, Lv T, Li M, Zhang Y, Xue T, et al. 2014. The lifespan-extending effects of Nymphaea hybrid root extract in the nematode Caenorhabditis elegans. Plant Foods for Human Nutrition 69:304−309

doi: 10.1007/s11130-014-0448-3
[92]

Che L, Wu X, Zheng X, Shen J, Lu F, et al. 2015. 香水莲花抑制大鼠前列腺增生的试验研究 [Effect of Nymphaea hybrid on prostatic hyperplasia in rats]. 中国食品学报 [Journal of Chinese Institute of Food Science and Technology] 15:28−33 (in Chinese)

doi: 10.16429/j.1009-7848.2015.02.005
[93]

Gautam S, Rahuja N, Ishrat N, Asthana RK, Mishra DK, et al. 2014. Nymphaea rubra ameliorates TNF-α-induced insulin resistance via suppression of c-Jun NH2-terminal kinase and nuclear factor-κB in the rat skeletal muscle cells. Applied Biochemistry and Biotechnology 174:2446−2457

doi: 10.1007/s12010-014-1192-8
[94]

Dong L, Zhou C, Zhao B, Lu F, Wu X, et al. 2019. 香水莲花提取物对小鼠高脂膳食诱导肥胖的预防作用 [Preventive effect of extracts from Nymphaea hybrid on mice with high fat diets-induced obesity]. 中国食品学报 [Journal of Chinese Institute of Food Science and Technology] 19:21−26 (in Chinese)

doi: 10.16429/j.1009-7848.2019.02.004
[95]

Antonisamy P, Subash-Babu P, Alshatwi AA, Aravinthan A, Ignacimuthu S, et al. 2014. Gastroprotective effect of nymphayol isolated from Nymphaea stellata (Willd.) flowers: contribution of antioxidant, anti-inflammatory and anti-apoptotic activities. Chemico-Biological Interactions 224:157−163

doi: 10.1016/j.cbi.2014.09.020
[96]

Bello FH, Maiha BB, Anuka JA. 2016. The effect of methanol rhizome extract of Nymphaea lotus Linn. (Nymphaeaceae) in animal models of diarrhoea. Journal of Ethnopharmacology 190:13−21

doi: 10.1016/j.jep.2016.05.036
[97]

Cheng JH, Lee SY, Lien YY, Lee MS, Sheu SC. 2012. Immunomodulating activity of Nymphaea rubra Roxb. extracts: activation of rat dendritic cells and improvement of the TH1 immune response. International Journal of Molecular Sciences 13:10722−10735

doi: 10.3390/ijms130910722
[98]

Bing SJ, Ha D, Kim MJ, Park E, Ahn G, et al. 2013. Geraniin down regulates gamma radiation-induced apoptosis by suppressing DNA damage. Food and Chemical Toxicology 57:147−153

doi: 10.1016/j.fct.2013.03.022
[99]

Behera SK, Mohapatra TK, Dash V. 2010. Anthelmintic activity of rhizomes of Nymphaea rubra Linn. Ancient Science of Life 29:33−36
[100]

Matsuda H, Morikawa T, Oda M, Asao Y, Yoshikawa M. 2003. Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum. Bioorganic & Medicinal Chemistry Letters 13:4445−4449

doi: 10.1016/j.bmcl.2003.09.019
[101]

Winer H, Ozer J, Shemer Y, Reichenstein I, Eilam-Frenkel B, et al. 2020. Nuphar lutea extracts exhibit anti-viral activity against the measles virus. Molecules 25:1657

doi: 10.3390/molecules25071657
[102]

Shmuel O, Rasti A, Zaknoun M, Astman N, Golan-Goldhirsh A, et al. 2024. Anti-Leishmania major properties of Nuphar lutea (yellow water lily) leaf extracts and purified 6,6' dihydroxythiobinupharidine (DTBN). Pathogens 13:384

doi: 10.3390/pathogens13050384
[103]

Liu C, Yu Q. 2004. 莼菜多糖粘胶降血糖作用的研究 [Study on the effect of Chuncai polysaccharide on lowering blood sugar]. 职业与健康 [Occupation and Health] 142−143 (in Chinese)

doi: 10.3969/j.issn.1004-1257.2004.06.141
[104]

Feng S, Luan D, Ning K, Shao P, Sun P. 2019. Ultrafiltration isolation, hypoglycemic activity analysis and structural characterization of polysaccharides from Brasenia schreberi. International Journal of Biological Macromolecules 135:141−151

doi: 10.1016/j.ijbiomac.2019.05.129
[105]

Luan D. 2020. 莼菜体外胶多糖降血糖组分分离及其降血糖机理研究 [Isolation and hypoglycemic mechanism effect of polysacchaide from Brasenia schreberi]. Thesis. Zhejiang University of Technology, China. 86 pp
[106]

Liu G, Feng S, Yan J, Luan D, Sun P, et al. 2022. Antidiabetic potential of polysaccharides from Brasenia schreberi regulating insulin signaling pathway and gut microbiota in type 2 diabetic mice. Current Research in Food Science 5:1465−1474

doi: 10.1016/j.crfs.2022.09.001
[107]

Wang Y, Zou Y, Fang Q, Feng R, Zhang J, et al. 2023. Polysaccharides from Brasenia schreberi with great antioxidant ability and the potential application in yogurt. Molecules 29:150

doi: 10.3390/molecules29010150
[108]

Wang Y, Wang B, Yan K, Liu L, Zhang J, et al. 2025. Polysaccharides from Brasenia schreberi alleviated the toxicity induced by acrylamide on cells and Caenorhabditis elegans. International Journal of Biological Macromolecules 309:142831

doi: 10.1016/j.ijbiomac.2025.142831
[109]

Chen J, Zhang Q, Yu G. 2020. 莼菜粗多糖对HeLa细胞生长影响的初步研究 [Preliminary study on the effect of crude polysaccharide from Brasenia schreberi on HeLa cell growth]. 中医学 [Traditional Chinese Medicine] 9:177−184 (in Chinese)

doi: 10.12677/TCM.2020.92023