[1]

Zhang L, Cao QQ, Granato D, Xu YQ, Ho CT. 2020. Association between chemistry and taste of tea: a review. Trends in Food Science & Technology 101:139−149

doi: 10.1016/j.tifs.2020.05.015
[2]

Tanaka T, Matsuo Y. 2020. Production mechanisms of black tea polyphenols. Chemical and Pharmaceutical Bulletin 68:1131−1142

doi: 10.1248/cpb.c20-00295
[3]

Roberts EAH. 1958. The chemistry of tea manufacture. Journal of the Science of Food and Agriculture 9:381−390

doi: 10.1002/jsfa.2740090701
[4]

Roberts EAH, Cartwright RA, Oldschool M. 1957. The phenolic substances of manufactured tea. I. — Fractionation and paper chromatography of water-soluble substances. Journal of the Science of Food and Agriculture 8:72−80

doi: 10.1002/jsfa.2740080203DigitalObjectIdentifier(DOI)
[5]

Zhang L, Ho CT, Zhou J, Santos JS, Armstrong L, et al. 2019. Chemistry and biological activities of processed Camellia sinensis teas: a comprehensive review. Comprehensive Reviews in Food Science and Food Safety 18:1474−1495

doi: 10.1111/1541-4337.12479
[6]

Long P, Rakariyatham K, Ho CT, Zhang L. 2023. Thearubigins: Formation, structure, health benefit and sensory property. Trends in Food Science & Technology 133:37−48

doi: 10.1016/j.tifs.2023.01.013
[7]

Guo X, Schwab W, Ho CT, Song C, Wan X. 2022. Characterization of the aroma profiles of oolong tea made from three tea cultivars by both GC–MS and GC-IMS. Food Chemistry 376:131933

doi: 10.1016/j.foodchem.2021.131933
[8]

Zhai X, Zhang L, Granvogl M, Ho CT, Wan X. 2022. Flavor of tea (Camellia sinensis): a review on odorants and analytical techniques. Comprehensive Reviews in Food Science and Food Safety 21:3867−3909

doi: 10.1111/1541-4337.12999
[9]

Ho CT, Zheng X, Li S. 2015. Tea aroma formation. Food Science and Human Wellness 4:9−27

doi: 10.1016/j.fshw.2015.04.001
[10]

Yue Y, Chu GX, Liu XS, Tang X, Wang W, et al. 2014. TMDB: a literature-curated database for small molecular compounds found from tea. BMC Plant Biology 14:243

doi: 10.1186/s12870-014-0243-1
[11]

Tanaka T, Betsumiya Y, Mine C, Kouno I. 2000. Theanaphthoquinone, a novel pigment oxidatively derived from theaflavin during tea-fermentation. Chemical Communications 1365−1366

doi: 10.1039/b003510f
[12]

Tanaka T, Inoue K, Betsumiya Y, Mine C, Kouno I. 2001. Two types of oxidative dimerization of the black tea polyphenol theaflavin. Journal of Agricultural and Food Chemistry 49:5785−5789

doi: 10.1021/jf010842x
[13]

Lai G, Wen M, Jiang Z, Zhou F, Huo HX, et al. 2023. Novel oxidation oligomer of chlorogenic acid and (−)-epigallocatechin and its quantitative analysis during the processing of keemun black tea. Journal of Agricultural and Food Chemistry 71:15745−15753

doi: 10.1021/acs.jafc.3c04571
[14]

Long P, Su S, Wen M, Ho CT, Han Z, et al. 2024. Novel pink pigments produced by thermal interaction of theaflavins, theanine, and glucose: color formation, isolation, and structural characterization. Journal of Agricultural and Food Chemistry 72:22303−22315

doi: 10.1021/acs.jafc.4c07072
[15]

Kawazoe R, Matsuo Y, Saito Y, Tanaka T. 2021. Stereochemistry of a cyclic epicatechin trimer with C3 symmetry produced by oxidative coupling. European Journal of Organic Chemistry 2021:777−781

doi: 10.1002/ejoc.202001579
[16]

Weerawatanakorn M, Hung WL, Pan MH, Li S, Li D, et al. 2015. Chemistry and health beneficial effects of oolong tea and theasinensins. Food Science and Human Wellness 4:133−146

doi: 10.1016/j.fshw.2015.10.002
[17]

Meng XH, Zhu HT, Yan H, Wang D, Yang CR, et al. 2018. C-8 N-Ethyl-2-pyrrolidinone-Substituted Flavan-3-ols from the Leaves of Camellia sinensis var. pubilimba. Journal of Agricultural and Food Chemistry 66:7150−7155

doi: 10.1021/acs.jafc.8b02066
[18]

Cheng J, Wu FH, Wang P, Ke JP, Wan XC, et al. 2018. Flavoalkaloids with a pyrrolidinone ring from Chinese ancient cultivated tea xi-Gui. Journal of Agricultural and Food Chemistry 66:7948−7957

doi: 10.1021/acs.jafc.8b02266
[19]

Jiang Z, Zhang H, Han Z, Zhai X, Qin C, et al. 2022. Study on in vitro preparation and taste properties of N-ethyl-2-pyrrolidinone-substituted flavan-3-ols. Journal of Agricultural and Food Chemistry 70:3832−3841

doi: 10.1021/acs.jafc.2c00798
[20]

Zhou J, Wu Y, Long P, Ho CT, Wang Y, et al. 2019. LC-MS-based metabolomics reveals the chemical changes of polyphenols during high-temperature roasting of large-leaf yellow tea. Journal of Agricultural and Food Chemistry 67:5405−5412

doi: 10.1021/acs.jafc.8b05062
[21]

Xiao Y, He C, Chen Y, Ho CT, Wu X, et al. 2022. UPLC–QQQ–MS/MS-based widely targeted metabolomic analysis reveals the effect of solid-state fermentation with Eurotium cristatum on the dynamic changes in the metabolite profile of dark tea. Food Chemistry 378:131999

doi: 10.1016/j.foodchem.2021.131999
[22]

Chen C, Li Y, Yu H, Xu Z, Tian H, et al. 2025. Mechanistic Insights into the interaction between aldehyde aroma compounds and β-Casein through Multi-Spectroscopy and molecular dynamics. Food Research International 200:115451

doi: 10.1016/j.foodres.2024.115451
[23]

Guo J, He Z, Wu S, Zeng M, Chen J. 2020. Effects of concentration of flavor compounds on interaction between soy protein isolate and flavor compounds. Food Hydrocolloids 100:105388

doi: 10.1016/j.foodhyd.2019.105388
[24]

Lyu J, Wang S, Ma Y, Xu Y, Tang K. 2024. Study on the interaction of tannins and salivary proteins affecting wine aroma volatility: Static HS-SPME and molecular dynamics simulation approaches. Food Research International 175:113809

doi: 10.1016/j.foodres.2023.113809
[25]

Feng ZJ, Xu QD, Chen N, Zeng WC. 2025. Regulation of catechins with different structure characteristics on the physicochemical properties of casein and the structure-activity relationship. Food Chemistry 467:142515

doi: 10.1016/j.foodchem.2024.142515
[26]

Haratifar S, Corredig M. 2014. Interactions between tea catechins and casein micelles and their impact on renneting functionality. Food Chemistry 143:27−32

doi: 10.1016/j.foodchem.2013.07.092
[27]

Cornelio P, Velasco C, Obrist M. 2021. Multisensory integration as per technological advances: a review. Frontiers in Neuroscience 15:652611

doi: 10.3389/fnins.2021.652611
[28]

Yi Z, Xie Y, Lv Z, Zhai Y, Zheng ML, et al. 2026. Multisensory integration through high-efficiency neuromorphic hardware. Nano Research 19:94908066

doi: 10.26599/NR.2025.94908066
[29]

Wei Y, Yu YY, Li YC, Zhong XY, Zou C, et al. 2026. Aroma compounds with enhanced sweet perception in tea infusions: screening, characterization, and sweetening mechanism. Journal of Advanced Research 81:1−12

doi: 10.1016/j.jare.2025.05.044
[30]

Arkhipov A, da Costa N, de Vries S, Bakken T, Bennett C, et al. 2025. Integrating multimodal data to understand cortical circuit architecture and function. Nature Neuroscience 28:717−730

doi: 10.1038/s41593-025-01904-7
[31]

Wen M, Zhu M, Han Z, Ho CT, Granato D, et al. 2023. Comprehensive applications of metabolomics on tea science and technology: Opportunities, hurdles, and perspectives. Comprehensive Reviews in Food Science and Food Safety 22:4890−4924

doi: 10.1111/1541-4337.13246
[32]

Zhou J, Cui G, Hu S, Zhang Z, Yang C, et al. 2020. Graph neural networks: a review of methods and applications. AI Open 1:57−81

doi: 10.1016/j.aiopen.2021.01.001
[33]

Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, et al. 2020. A deep learning approach to antibiotic discovery. Cell 180:688−702.e13

doi: 10.1016/j.cell.2020.01.021
[34]

Chen X, Zhang ZJ, Hong X, Ackermann L. 2025. Integrating a multitask graph neural network with DFT calculations for site-selectivity prediction of arenes and mechanistic knowledge generation. Nature Synthesis 4:877−887

doi: 10.1038/s44160-025-00770-2
[35]

Sanchez-Lengeling B, Reif E, Pearce A, Wiltschko AB. 2021. A gentle introduction to graph neural networks. Distill

doi: 10.23915/distill.00033