[1]

Shahrajabian MH, Sun W, Cheng Q. 2019. Clinical aspects and health benefits of ginger (Zingiber officinale) in both traditional Chinese medicine and modern industry. Acta Agriculturae Scandinavica, Section B — Soil & Plant Science 69(6):546−556

doi: 10.1080/09064710.2019.1606930
[2]

Shaukat MN, Nazir A, Fallico B. 2023. Ginger bioactives: a comprehensive review of health benefits and potential food applications. Antioxidants 12(11):2015

doi: 10.3390/antiox12112015
[3]

Mahboubi M. 2019. Zingiber officinale Rosc. essential oil, a review on its composition and bioactivity. Clinical Phytoscience 5(1):6

doi: 10.1186/s40816-018-0097-4
[4]

Mahomoodally MF, Aumeeruddy MZ, Rengasamy KRR, Roshan S, Hammad S, et al. 2021. Ginger and its active compounds in cancer therapy: from folk uses to nano-therapeutic applications. Seminars in Cancer Biology 69:140−149

doi: 10.1016/j.semcancer.2019.08.009
[5]

Abd El-Hack ME, Alagawany M, Shaheen H, Samak D, Othman SI, et al. 2020. Ginger and its derivatives as promising alternatives to antibiotics in poultry feed. Animals 10(3):452

doi: 10.3390/ani10030452
[6]

Edo GI, Igbuku UA, Makia RS, Isoje EF, Gaaz TS, et al. 2025. Phytochemical profile, therapeutic potentials, nutritional composition, and food applications of ginger: a comprehensive review. Discover Food 5(1):25

doi: 10.1007/s44187-025-00280-2
[7]

Edo GI, Samuel PO, Ossai S, Nwachukwu SC, Okolie MC, et al. 2023. Phytochemistry and pharmacological compounds present in scent leaf: a review. Food Chemistry Advances 3:100300

doi: 10.1016/j.focha.2023.100300
[8]

Maghraby YR, Labib RM, Sobeh M, Farag MA. 2023. Gingerols and shogaols: a multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications. Food Chemistry: X 20:100947

doi: 10.1016/j.fochx.2023.100947
[9]

Sang S, Snook HD, Tareq FS, Fasina Y. 2020. Precision research on ginger: the type of ginger matters. Journal of Agricultural and Food Chemistry 68(32):8517−8523

doi: 10.1021/acs.jafc.0c03888
[10]

Alolga RN, Wang F, Zhang X, Li J, Tran L-SP, et al. 2022. Bioactive compounds from the zingiberaceae family with known antioxidant activities for possible therapeutic uses. Antioxidants 11(7):1281

doi: 10.3390/antiox11071281
[11]

Pázmándi K, Ágics B, Szöllősi AG, Bácsi A, Fekete T. 2024. Ginger-derived bioactive compounds attenuate the toll-like receptor mediated responses of human dendritic cells. European Journal of Pharmacology 967:176399

doi: 10.1016/j.ejphar.2024.176399
[12]

El-Sabrout K, Khalifah A, Mishra B. 2023. Application of botanical products as nutraceutical feed additives for improving poultry health and production. Veterinary World 16(2):369−379

doi: 10.14202/vetworld.2023.369-379
[13]

Derese DB, Sun H, Xiong X, Li Z, Malyar RM, et al. 2025. Effects of dietary ginger (Zingiber officinale) rhizome powder supplementation on productive performance, egg quality, antioxidant capacity, and hepato-intestinal morphology in pre-peak xiaoshan laying hens. Animals 15(15):2315

doi: 10.3390/ani15152315
[14]

Dosoky WM, Farag SA, Almasmoum HA, Khisheerah NSM, Youssef IM, et al. 2023. Influences of dietary supplementation of ginger powder and frankincense oil on productive performance, blood biochemical parameters, oxidative status and tissues histomorphology of laying Japanese quail. Poultry Science 102(11):102988

doi: 10.1016/j.psj.2023.102988
[15]

Apalowo OO, Minor RC, Adetunji AO, Ekunseitan DA, Fasina YO. 2024. Effect of ginger root extract on intestinal oxidative status and mucosal morphometrics in broiler chickens. Animals 14(7):1084

doi: 10.3390/ani14071084
[16]

Dosu G, Obanla TO, Zhang S, Sang S, Adetunji AO, et al. 2023. Supplementation of ginger root extract into broiler chicken diet: effects on growth performance and immunocompetence. Poultry Science 102(10):102897

doi: 10.1016/j.psj.2023.102897
[17]

Tong Y, Wang Y, Zhang J, Guo Y, Yuan T, et al. 2025. Comprehensive study on the impact of ginger extract on laying performance, egg quality, inflammatory responses, intestinal barrier function, and cecal microbiome and resistome in laying hens. Poultry Science 104(10):105448

doi: 10.1016/j.psj.2025.105448
[18]

Wen C, Gu Y, Tao Z, Cheng Z, Wang T, et al. 2019. Effects of ginger extract on laying performance, egg quality, and antioxidant status of laying hens. Animals 9(11):857

doi: 10.3390/ani9110857
[19]

Liu J, Jin Y, Yang J. 2022. Influence of spent ginger yeast cultures on the production performance, egg quality, serum composition, and intestinal microbiota of laying hens. Animal Bioscience 35(8):1205−1214

doi: 10.5713/ab.21.0514
[20]

Herve T, Raphaël KJ, Ferdinand N, Victor Herman N, Willy Marvel NM, et al. 2019. Effects of ginger ( Zingiber officinale, Roscoe) essential oil on growth and laying performances, serum metabolites, and egg yolk antioxidant and cholesterol status in laying Japanese quail. Journal of Veterinary Medicine 2019:7857504

doi: 10.1155/2019/7857504
[21]

Maisaroh, Hartono LK, Pongtuluran OB, Atmaji P, Yuliani S, et al. 2025. Freeze- and oven-drying of red ginger juice (Zingiber officinale var. Rubrum): a comparative study on physicochemical properties, bioactive retention, and microstructural characteristics. South African Journal of Chemical Engineering 54:254−265

doi: 10.1016/j.sajce.2025.08.004
[22]

Hu W, Yu A, Wang S, Bai Q, Tang H, et al. 2023. Extraction, purification, structural characteristics, biological activities, and applications of the polysaccharides from Zingiber officinale Roscoe. (ginger): a review. Molecules 28(9):3855

doi: 10.3390/molecules28093855
[23]

Shaukat MN, Fallico B, Nazir A. 2024. Impact of air-drying temperatures on drying kinetics, physicochemical properties, and bioactive profile of ginger. Foods 13(7):1096

doi: 10.3390/foods13071096
[24]

Nemati Z, Moradi Z, Alirezalu K, Besharati M, Raposo A. 2021. Impact of ginger root powder dietary supplement on productive performance, egg quality, antioxidant status and blood parameters in laying Japanese quails. International Journal of Environmental Research and Public Health 18(6):2995

doi: 10.3390/ijerph18062995
[25]

Ayustaningwarno F, Anjani G, Ayu AM, Fogliano V. 2024. A critical review of ginger's (Zingiber officinale) antioxidant, anti-inflammatory, and immunomodulatory activities. Frontiers in Nutrition 11:1364836

doi: 10.3389/fnut.2024.1364836
[26]

Plana L, Marhuenda J, Arcusa R, García-Muñoz AM, Ballester P, et al. 2025. Characterization, antioxidant capacity, and in vitro bioaccessibility of ginger (Zingiber officinale Roscoe) in different pharmaceutical formulations. Antioxidants 14(7):873

doi: 10.3390/antiox14070873
[27]

Ozkur M, Benlier N, Takan I, Vasileiou C, Georgakilas AG, et al. 2022. Ginger for healthy ageing: a systematic review on current evidence of its antioxidant, anti‐inflammatory, and anticancer properties. Oxidative Medicine and Cellular Longevity 2022:4748447

doi: 10.1155/2022/4748447
[28]

Spyrou A, Batista MGF, Corazza ML, Papadaki M, Antonopoulou M. 2024. Extraction of high value products from Zingiber officinale Roscoe (ginger) and utilization of residual biomass. Molecules 29(4):871

doi: 10.3390/molecules29040871
[29]

Sulejmanović M, Panić M, Redovniković IR, Milić N, Drljača J, et al. 2025. Sustainable isolation of ginger (Zingiber officinale) herbal dust bioactive compounds with favorable toxicological profile employing natural deep eutectic solvents (NADES). Food Chemistry 464:141545

doi: 10.1016/j.foodchem.2024.141545
[30]

Zhang S, Fasina Y, Dosu G, Sang S. 2023. Absorption and metabolism of ginger compounds in broiler chicks. Journal of Agricultural and Food Chemistry 71(37):13757−13767

doi: 10.1021/acs.jafc.3c01857
[31]

An S, Liu G, Guo X, An Y, Wang R. 2019. Ginger extract enhances antioxidant ability and immunity of layers. Animal Nutrition 5(4):407−409

doi: 10.1016/j.aninu.2019.05.003
[32]

Mohammed HA, Sulaiman GM, Khan RA, Al-Saffar AZ, Mohsin MH, et al. 2024. Essential oils pharmacological activity: Chemical markers, biogenesis, plant sources, and commercial products. Process Biochemistry 144:112−132

doi: 10.1016/j.procbio.2024.05.021
[33]

Nabi MHB, Ahmed MM, Mia MS, Islam S, Zzaman W. 2025. Essential oils: advances in extraction techniques, chemical composition, bioactivities, and emerging applications. Food Chemistry Advances 8:101048

doi: 10.1016/j.focha.2025.101048
[34]

Abd El-Hack ME, AboElMaati MF, Abusudah WF, Awlya OF, Almohmadi NH, et al. 2024. Consequences of dietary cinnamon and ginger oils supplementation on blood biochemical parameters, oxidative status, and tissue histomorphology of growing Japanese quails. Poultry Science 103(2):103314

doi: 10.1016/j.psj.2023.103314
[35]

De Freitas BC, Queiroz PA, Baldin VP, Do Amaral PH, Rodrigues LL, et al. 2020. (−)-Camphene-based derivatives as potential antibacterial agents against Staphylococcus aureus and Enterococcus spp. Future Microbiology 15(16):1527−1534

doi: 10.2217/fmb-2020-0131
[36]

Wang X, Shen Y, Thakur K, Han J, Zhang JG, et al. 2020. Antibacterial activity and mechanism of ginger essential oil against Escherichia coli and Staphylococcus aureus. Molecules 25(17):3955

doi: 10.3390/molecules25173955
[37]

Zhang C, Xie Y, Qiu W, Mei J, Xie J. 2023. Antibacterial and antibiofilm efficacy and mechanism of ginger (Zingiber officinale) essential oil against Shewanella putrefaciens. Plants 12(8):1720

doi: 10.3390/plants12081720
[38]

Movahedi F, Nirmal N, Wang P, Jin H, Grøndahl L, et al. 2024. Recent advances in essential oils and their nanoformulations for poultry feed. Journal of Animal Science and Biotechnology 15(1):110

doi: 10.1186/s40104-024-01067-8
[39]

Dupuis V, Cerbu C, Witkowski L, Potarniche AV, Timar MC, et al. 2022. Nanodelivery of essential oils as efficient tools against antimicrobial resistance: a review of the type and physical-chemical properties of the delivery systems and applications. Drug Delivery 29(1):1007−1024

doi: 10.1080/10717544.2022.2056663
[40]

Moharreri M, Vakili R, Oskoueian E, Rajabzadeh G. 2021. Phytobiotic role of essential oil-loaded microcapsules in improving the health parameters in Clostridium perfringens-infected broiler chickens. Italian Journal of Animal Science 20(1):2075−2085

doi: 10.1080/1828051X.2021.1993093
[41]

Irawan A, Hidayat C, Jayanegara A, Ratriyanto A. 2021. Essential oils as growth-promoting additives on performance, nutrient digestibility, cecal microbes, and serum metabolites of broiler chickens: a meta-analysis. Animal Bioscience 34(9):1499−1513

doi: 10.5713/ab.20.0668
[42]

Kaur H, Kaur G, Ali SA. 2022. Dairy-based probiotic-fermented functional foods: an update on their health-promoting properties. Fermentation 8(9):425

doi: 10.3390/fermentation8090425
[43]

Kayath CA, Ibala Zamba A, Mokémiabeka SN, Opa-Iloy M, Elenga Wilson PS, et al. 2020. Synergic involvements of microorganisms in the biomedical increase of polyphenols and flavonoids during the fermentation of ginger juice. International Journal of Microbiology 2020:8417693

doi: 10.1155/2020/8417693
[44]

Peng S, Yao J, Liu Y, Duan D, Zhang X, et al. 2015. Activation of Nrf2 target enzymes conferring protection against oxidative stress in PC12 cells by ginger principal constituent 6-shogaol. Food & Function 6(8):2813−2823

doi: 10.1039/C5FO00214A
[45]

Latif A, Shehzad A, Niazi S, Zahid A, Ashraf W, et al. 2023. Probiotics: mechanism of action, health benefits and their application in food industries. Frontiers in Microbiology 14:1216674

doi: 10.3389/fmicb.2023.1216674
[46]

Sharma R, Garg P, Kumar P, Bhatia SK, Kulshrestha S. 2020. Microbial fermentation and its role in quality improvement of fermented foods. Fermentation 6(4):106

doi: 10.3390/fermentation6040106
[47]

Voidarou C, Antoniadou Μ, Rozos G, Tzora A, Skoufos I, et al. 2021. Fermentative foods: microbiology, biochemistry, potential human health benefits and public health issues. Foods 10(1):69

doi: 10.3390/foods10010069
[48]

Kim JE, Park KH, Park J, Kim BS, Kim GS, et al. 2025. Immunomodulatory potential of 6-gingerol and 6-shogaol in Lactobacillus plantarum-fermented Zingiber officinale extract on murine macrophages. International Journal of Molecular Sciences 26(5):2159

doi: 10.3390/ijms26052159
[49]

Kujero M, Adeyemi OA, Njoku C, Sogunle O, Sobayo R, et al. 2024. Reproductive and physiological responses and egg quality traits of isa brown chickens fed diets fed ginger or turmeric powder under tropical hot environments. Archives of Veterinary Science 29(2):95238

doi: 10.5380/avs.v29i2.95238
[50]

Majeed Z, Mustafa N. 2023. Impact laying times of broiler breeder supplement with aromatic oils (Miarom) in drinking water on hatchability, maternal immunity and serum antioxidant and antioxidant statues hatched chicks. Tikrit Journal for Agricultural Sciences 23(1):44−50

doi: 10.25130/tjas.23.1.6
[51]

Pasri P, Rakngam S, Gérard N, Mermillod P, Khempaka S. 2024. Synthetic and phytogenic antioxidants improve productive performance, antioxidant activity, gene expression, and offspring quality in breeder hens subjected to heat stress. Poultry Science 103(3):103390

doi: 10.1016/j.psj.2023.103390
[52]

Sytykiewicz H, Goławska S, Łukasik I. 2025. New insights into the synergistic bioactivities of Zingiber officinale (Rosc.) and Humulus lupulus (L.) essential oils: targeting tyrosinase inhibition and antioxidant mechanisms. Molecules 30(15):3294

doi: 10.3390/molecules30153294
[53]

Olayemi WA, Rabiu LA, Akapo AO, Oso OA, Ogunleye T. 2020. Interaction effects of dietary ginger Zingiber officinale and yeast Sacharomyces cerevisiae supplementation on performance, carcass yield and gut micro flora of broiler chickens. Nigerian Journal of Animal Production 47(2):89−99

doi: 10.51791/njap.v47i2.104
[54]

Ibtisham F, Nawab A, Niu Y, Wang Z, Wu J, et al. 2019. The effect of ginger powder and Chinese herbal medicine on production performance, serum metabolites and antioxidant status of laying hens under heat-stress condition. Journal of Thermal Biology 81:20−24

doi: 10.1016/j.jtherbio.2019.02.002
[55]

Adetunji AO, Price J, Owusu H, Adewale EF, Adesina PA, et al. 2025. Mechanisms by which phytogenic extracts enhance livestock reproductive health: current insights and future directions. Frontiers in Veterinary Science 12:1568577

doi: 10.3389/fvets.2025.1568577
[56]

Ajao AM, Oso AO, Lala AO, Olowofeso O, Adeniran AD. 2020. Effect of varying level of ginger powder in the diet of starter turkeys on performance, haematological and serum biochemical indices. Nigerian Journal of Animal Production 45(1):212

doi: 10.51791/njap.v45i1.330
[57]

Abubakar JO, Uchechi NC, Olayinka Abosede O, Oladimeji Samuel T. 2023. Role of oral phytogenic supplementation to protect cardiac, hepatic, nephrotic, and splenic oxidative stress in broiler chickens. Translational Animal Science 7(1):txad106

doi: 10.1093/tas/txad106
[58]

Ajayi EA, Sholademi EL, Abu OA, Iheanacho GC, Odoemena EC, et al. 2024. Growth performance of broiler chickens on dietary supplementation of garlic and ginger powder. American Journal of Agricultural Science, Engineering, and Technology 8(3):10−17

doi: 10.54536/ajaset.v8i3.3491
[59]

Brouklogiannis IP, Anagnostopoulos EC, Griela E, Paraskeuas VV, Mountzouris KC. 2023. Dietary phytogenic inclusion level affects production performance and expression of ovarian cytoprotective genes in laying hens. Poultry Science 102(4):102508

doi: 10.1016/j.psj.2023.102508
[60]

Bayril T, Akdemir F, Gürgöze S, Orhan C. 2023. Effect of dietary stevia and ginger extracts on laying performance, fertility, hatchability, and serum biochemical parameters in laying Japanese quails exposed to heat stress. Journal of Animal and Feed Sciences 32(3):289−296

doi: 10.22358/jafs/160328/2023
[61]

Kousar S, Chand N, Naz S, Alhidary IA, Sifa D, et al. 2024. In vitro and in vivo effects of methanolic extract of dietary ginger (Zingiber officinale) and onion (Allium cepa) supplementation on growth performance and fecal microbiota in Escherichia coli infected broiler chickens. Livestock Science 281:105416

doi: 10.1016/j.livsci.2024.105416
[62]

Li Z, Qumar M, Irfan M, Khan MT, Faran G, et al. 2025. Impact of dietary turmeric and ginger powder on performance, serum chemistry and gut microbiota in laying hens. Journal of Applied Poultry Research 34(4):100605

doi: 10.1016/j.japr.2025.100605
[63]

Al-Khalaifah H, Al-Nasser A, Al-Surrayai T, Sultan H, Al-Attal D, et al. 2022. Effect of ginger powder on production performance, antioxidant status, hematological parameters, digestibility, and plasma cholesterol content in broiler chickens. Animals 12(7):901

doi: 10.3390/ani12070901
[64]

Asghar MU, Rahman A, Hayat Z, Rafique MK, Badar IH, et al. 2023. Exploration of Zingiber officinale effects on growth performance, immunity and gut morphology in broilers. Brazilian Journal of Biology 83:e250296

doi: 10.1590/1519-6984.250296
[65]

Authaida S, Chankitisakul V, Ratchamak R, Pimpa J, Koedkanmark T, et al. 2024. The effect of Thai ginger (Kaempferia parviflora) extract orally administration on sperm production, semen preservation, and fertility in Thai native chickens under heat stress. Poultry Science 103(2):103372

doi: 10.1016/j.psj.2023.103372
[66]

Herawati H, Anisa AK, Widiatmoko KD, Alam SSP, Diari IA, et al. 2022. Effect of red ginger powder (Zingiber officinale var. rubrum) as a feed additive for starter and finisher broiler chicken to increase immunoglobulin A and immunoglobulin Y expression and to prevent intestinal injury due to Salmonella enteritidis infection. Veterinary World 15(6):1506–1514

[67]

Nemati Z, Dehgani P, Karimi A, Amirdahri S, Kianifard D. 2023. Effects of ginger (Zingiber officinale) supplementation on testicular histology, semen characteristic, blood plasma parameters and reproductive performance in aged broiler breeder roosters. Journal of Animal Physiology and Animal Nutrition 107(3):907−919

doi: 10.1111/jpn.13779
[68]

Ogbu CC, Ndifereke S, Ogbu NN. 2024. Genotype and dietary supplementation of ginger (Zingibar officinale) rhizome powder affect egg quality traits of layer chickens. Discover Animals 1(1):17

doi: 10.1007/s44338-024-00010-5
[69]

Yang Z, Guo Z, Yan J, Xie J. 2024. Nutritional components, phytochemical compositions, biological properties, and potential food applications of ginger (Zingiber officinale): a comprehensive review. Journal of Food Composition and Analysis 128:106057

doi: 10.1016/j.jfca.2024.106057
[70]

Mustafa I, Chin NL, Fakurazi S, Palanisamy A. 2019. Comparison of phytochemicals, antioxidant and anti-inflammatory properties of sun-, oven- and freeze-dried ginger extracts. Foods 8(10):456

doi: 10.3390/foods8100456
[71]

Ma RH, Ni ZJ, Zhu YY, Thakur K, Zhang F, et al. 2021. A recent update on the multifaceted health benefits associated with ginger and its bioactive components. Food & Function 12(2):519−542

doi: 10.1039/D0FO02834G
[72]

Zhang M, Zhao R, Wang D, Wang L, Zhang Q, et al. 2021. Ginger (Zingiber officinale Rosc.) and its bioactive components are potential resources for health beneficial agents. Phytotherapy Research 35(2):711−742

doi: 10.1002/ptr.6858
[73]

Mak KK, Shiming Z, Sakirolla R, Balijepalli MK, Dinkova Kostova AT, et al. 2023. Synthesis of new shogaol analogues as NRF2 activators and evaluation of their anti-inflammatory activity, modes of action and metabolic stability. Antioxidants 12(2):475

doi: 10.3390/antiox12020475
[74]

Yang AY, Kim K, Kwon HH, Leem J, Song JE. 2024. 6-Shogaol ameliorates liver inflammation and fibrosis in mice on a methionine- and choline-deficient diet by inhibiting oxidative stress, cell death, and endoplasmic reticulum stress. Molecules 29(2):419

doi: 10.3390/molecules29020419
[75]

Zong X, Ding Q, Liu X, Liu Q, Song S, et al. 2023. Preventive effect of 6-shogaol on D-galactosamine induced hepatotoxicity through NF-κB/MAPK signaling pathway in rats. Physiological Research 72(4):445–454

doi: 10.33549/physiolres.935092
[76]

Farombi EO, Ajayi BO, Ajeigbe OF, Maruf OR, Anyebe DA, et al. 2025. Mechanistic exploration of 6-shogaol's preventive effects on azoxymethane and dextran sulfate sodium-induced colorectal cancer: involvement of cell proliferation, apoptosis, carcinoembryonic antigen, wingless-related integration site signaling, and oxido-inflammation. Toxicology Mechanisms and Methods 35(1):1−10

doi: 10.1080/15376516.2024.2381798
[77]

Yan X, Luo J, Chen X, Wang L, Xu Z, et al. 2025. 6‐Shogaol reduces renal macrophage infiltration by targeting the sting pathway to alleviate cisplatin induced renal injury. Phytotherapy Research 39(9):4081−4093

doi: 10.1002/ptr.70053
[78]

Mao QQ, Xu XY, Cao SY, Gan RY, Corke H, et al. 2019. Bioactive compounds and bioactivities of ginger (Zingiber officinale Roscoe). Foods 8(6):185

doi: 10.3390/foods8060185
[79]

Sulieman AME, Ibrahim SM, Alshammari M, Abdulaziz F, Idriss H, et al. 2024. Zingiber officinale uncovered: integrating experimental and computational approaches to antibacterial and phytochemical profiling. Pharmaceuticals 17(11):1551

doi: 10.3390/ph17111551
[80]

Arcusa R, Villaño D, Marhuenda J, Cano M, Cerdà B, et al. 2022. Potential role of ginger (Zingiber officinale Roscoe) in the prevention of neurodegenerative diseases. Frontiers in Nutrition 9:809621

doi: 10.3389/fnut.2022.809621
[81]

Rashpa S, Chadha J, Khullar L, Sharma B, Harjai K. 2025. Revisiting the multifaceted phytochemical: an updated review on therapeutic potential, pharmaceutical formulations, pre-clinical, and clinical trials of zingerone. European Journal of Medicinal Chemistry 297:117971

[82]

Dutta A, Gurusubramanian G, Roy VK. 2025. Effects of zingerone supplementation on ovarian steroidogenesis and folliculogenesis in mouse. The Journal of Nutritional Biochemistry 145:110043

doi: 10.1016/j.jnutbio.2025.110043
[83]

Jerang M, Gurusubramanian G, Singh VP, Roy VK. 2025. Zingerone modulates the circulating steroids hormone levels and testicular steroidogenic markers expression in mice: an in vivo and in silico study. The Journal of Steroid Biochemistry and Molecular Biology 251:106748

doi: 10.1016/j.jsbmb.2025.106748
[84]

Jin S, Shi J, Zhao M, Liu X, Yang K, et al. 2025. The influence of dietary supplementation with ginger ethanol extract on laying hens' production performance, antioxidant capacity, and gut microbiota. Frontiers in Veterinary Science 12:1652982

doi: 10.3389/fvets.2025.1652982
[85]

Gholami‐Ahangaran M, Karimi‐Dehkordi M, Akbari Javar A, Haj Salehi M, Ostadpoor M. 2021. A systematic review on the effect of ginger (Zingiber officinale ) on improvement of biological and fertility indices of sperm in laboratory animals, poultry and humans. Veterinary Medicine and Science 7(5):1959−1969

doi: 10.1002/vms3.538
[86]

Safavipour S, Tabeidian SA, Toghyani M, Foroozandeh Shahraki AD, Ghalamkari G, et al. 2022. Laying performance, egg quality, fertility, nutrient digestibility, digestive enzymes activity, gut microbiota, intestinal morphology, antioxidant capacity, mucosal immunity, and cytokine levels in meat-type Japanese quail breeders fed different phytogenic levels. Research in Veterinary Science 153:74−87

doi: 10.1016/j.rvsc.2022.10.017
[87]

Tchoffo H, Ngoula F, Kana JR, Kenfack A, Ngoumtsop VH, et al. 2017. Effects of ginger (Zingiber officinale) rhizomes essential oil on some reproductive parameters in laying Japanese quail (Coturnix coturnix japonica). Advances in Reproductive Sciences 5:64−74

doi: 10.4236/arsci.2017.54008
[88]

Hüseyin Ipçak H. 2023. The role of phytogenic feed additives in modulating poultry nutritional physiology and genomics. In Veterinary Medicine and Science, eds. Gonzalez Ronquillo M, Pereira RMLN. London: IntechOpen. doi: 10.5772/intechopen.112082

[89]

Jegede P, Yakubu A, Musa IS, Vincent ST, Shoyombo AJ, et al. 2024. Fertility, hatchability, and prediction of egg weight from egg quality indices of Nigerian indigenous and exotic helmeted guinea fowls. Poultry 4(1):1

doi: 10.3390/poultry4010001
[90]

Fathi M, Abou-Emera O, Al-Homidan I, Galal A, Rayan G. 2022. Effect of genotype and egg weight on hatchability properties and embryonic mortality pattern of native chicken populations. Poultry Science 101(11):102129

doi: 10.1016/j.psj.2022.102129
[91]

Rebolledo OFP, López MFA, Rivera JAH, Canul AC, Isaias GT, et al. 2023. Effect of the line and age of female broiler breeder on hatchability performance of eggs. Brazilian Journal of Poultry Science 25(1):1639

doi: 10.1590/1806-9061-2022-1639
[92]

Nowaczewski S, Babuszkiewicz M, Szablewski T, Stuper-Szablewska K, Cegielska-Radziejewska R, et al. 2022. Effect of weight and storage time of broiler breeders' eggs on morphology and biochemical features of eggs, embryogenesis, hatchability, and chick quality. Animal 16(7):100564

doi: 10.1016/j.animal.2022.100564
[93]

Zhang J, Zhang J, Li K, Fu X, Liang Y, et al. 2025. Kaempferol and vitamin e improve production performance by linking the gut–uterus axis through the reproductive hormones and microbiota of late-laying hens. Animals 15(1):15

doi: 10.3390/ani15010015
[94]

Shen M, Li T, Lu J, Qu L, Wang K, et al. 2022. Effects of supplementation of Moringa oleifera leaf powder on some reproductive performance in laying hens. Brazilian Journal of Poultry Science 24(2):1537

doi: 10.1590/1806-9061-2021-1537
[95]

Cao X, Amevor FK, Du X, Wu Y, Xu D, et al. 2024. Supplementation of the combination of quercetin and vitamin E alleviates the effects of heat stress on the uterine function and hormone synthesis in laying hens. Animals 14(11):1554

doi: 10.3390/ani14111554
[96]

Liu M, Lu Y, Gao P, Xie X, Li D, et al. 2020. Effect of curcumin on laying performance, egg quality, endocrine hormones, and immune activity in heat-stressed hens. Poultry Science 99(4):2196−2202

doi: 10.1016/j.psj.2019.12.001
[97]

Ogbu CC, Ndifereke S, Ogbu NN. 2024. Genotype and ginger (Zingibar officinale) rhizome powder dietary supplementation affect egg quality indices of aged layer chickens. Discover Animals 1:17

doi: 10.21203/rs.3.rs-3753497/v1
[98]

Lu X, Chang X, Zhang H, Wang J, Qiu K, et al. 2023. Effects of dietary rare earth chitosan chelate on performance, egg quality, immune and antioxidant capacity, and intestinal digestive enzyme activity of laying hens. Polymers 15(7):1600

doi: 10.3390/polym15071600