A Differential Depth Sequencing Method, SPRE‐Seq, for Enhancing Targeted Region Coverage in Hybridization Capture‐Based NGS

Hui‐Juan Chen; Bing Wang; Yi‐Ran Zhang; Xue‐Na Yao; Chun‐Yan Yang; He‐Nan Dong; Li‐Li Cai; Dong‐Jie Fan; Qi‐Ming Zhou; Hui‐Juan Chen; Bing Wang; Yi‐Ran Zhang; Xue‐Na Yao; Chun‐Yan Yang; He‐Nan Dong; Li‐Li Cai; Dong‐Jie Fan; Qi‐Ming Zhou

doi:10.1002/elsc.70047

2025 Volume 25

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RESEARCH ARTICLE Open Access

A Differential Depth Sequencing Method, SPRE‐Seq, for Enhancing Targeted Region Coverage in Hybridization Capture‐Based NGS

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Published online: 24 October 2025
Engineering in Life Sciences 25(10), Article number: 10.1002/elsc.70047 (2025) | Cite this article

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Copyright: © 2025 by the author(s). Exclusive Licensee Maximum Academic Press, Fayetteville, GA. This article is an open access article distributed under Creative Commons Attribution License (CC BY 4.0), visit https://creativecommons.org/licenses/by/4.0/.

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Hui‐Juan Chen, Bing Wang, Yi‐Ran Zhang, Xue‐Na Yao, Chun‐Yan Yang, He‐Nan Dong, Li‐Li Cai, Dong‐Jie Fan, Qi‐Ming Zhou. 2025. A Differential Depth Sequencing Method, SPRE‐Seq, for Enhancing Targeted Region Coverage in Hybridization Capture‐Based NGS. Engineering in Life Sciences. 25:47 doi: 10.1002/elsc.70047

Hui‐Juan Chen, Bing Wang, Yi‐Ran Zhang, Xue‐Na Yao, Chun‐Yan Yang, He‐Nan Dong, Li‐Li Cai, Dong‐Jie Fan, Qi‐Ming Zhou. 2025. A Differential Depth Sequencing Method, SPRE‐Seq, for Enhancing Targeted Region Coverage in Hybridization Capture‐Based NGS. Engineering in Life Sciences. 25:47 doi: 10.1002/elsc.70047

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