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2020 Volume 7
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CASE REPORT   Open Access    

Long-Term Survival under Arterial Chemoembolization and Sorafenib of a Patient with Hepatocellular Carcinoma and Tumor Atrial Thrombus: A Case Report and Literature Review

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  • Corresponding author: Andreas Mavroudis First Department of Internal Medicine, Laiko General Hospital Medical School of National and Kapodistrian University of Athens Agiou Thoma 17, GR–11527 Athens (Greece) andreasmavroudis89@gmail.com 
  • Hepatocellular carcinoma (HCC) is considered to be the fourth most frequent cause of cancer-associated death globally. HCC might be associated, especially in advanced stages, with the formation of tumor thrombus (TT), which can be located in the portal vein, as well as in hepatic and/or inferior vena cava (IVC) veins. Nevertheless, the extension of TT to the right atrium (RA) is infrequent with an unfavorable prognosis. We present a rare case of a male patient with HCC and IVC TT extending to the RA. The atrial thrombus was the first manifestation of HCC diagnosed by cardiac ultrasound. So far, the patient has undergone 4 courses of transarterial chemoembolization in combination with systemic therapy with sorafenib, and under this therapeutic approach long-term survival has been achieved.
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    Andreas Mavroudis, Evangelos Cholongitas. 2020. Long-Term Survival under Arterial Chemoembolization and Sorafenib of a Patient with Hepatocellular Carcinoma and Tumor Atrial Thrombus: A Case Report and Literature Review. Gastrointestinal Tumors. 7:186 doi: 10.1159/000509186
    Andreas Mavroudis, Evangelos Cholongitas. 2020. Long-Term Survival under Arterial Chemoembolization and Sorafenib of a Patient with Hepatocellular Carcinoma and Tumor Atrial Thrombus: A Case Report and Literature Review. Gastrointestinal Tumors. 7:186 doi: 10.1159/000509186

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Case Report   Open Access    

Long-Term Survival under Arterial Chemoembolization and Sorafenib of a Patient with Hepatocellular Carcinoma and Tumor Atrial Thrombus: A Case Report and Literature Review

  • Corresponding author: Andreas Mavroudis First Department of Internal Medicine, Laiko General Hospital Medical School of National and Kapodistrian University of Athens Agiou Thoma 17, GR–11527 Athens (Greece) andreasmavroudis89@gmail.com 
Gastrointestinal Tumors  7 Article number: 10.1159/000509186  (2020)  |  Cite this article

Abstract: Hepatocellular carcinoma (HCC) is considered to be the fourth most frequent cause of cancer-associated death globally. HCC might be associated, especially in advanced stages, with the formation of tumor thrombus (TT), which can be located in the portal vein, as well as in hepatic and/or inferior vena cava (IVC) veins. Nevertheless, the extension of TT to the right atrium (RA) is infrequent with an unfavorable prognosis. We present a rare case of a male patient with HCC and IVC TT extending to the RA. The atrial thrombus was the first manifestation of HCC diagnosed by cardiac ultrasound. So far, the patient has undergone 4 courses of transarterial chemoembolization in combination with systemic therapy with sorafenib, and under this therapeutic approach long-term survival has been achieved.

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    Cite this article
    Andreas Mavroudis, Evangelos Cholongitas. 2020. Long-Term Survival under Arterial Chemoembolization and Sorafenib of a Patient with Hepatocellular Carcinoma and Tumor Atrial Thrombus: A Case Report and Literature Review. Gastrointestinal Tumors. 7:186 doi: 10.1159/000509186
    Andreas Mavroudis, Evangelos Cholongitas. 2020. Long-Term Survival under Arterial Chemoembolization and Sorafenib of a Patient with Hepatocellular Carcinoma and Tumor Atrial Thrombus: A Case Report and Literature Review. Gastrointestinal Tumors. 7:186 doi: 10.1159/000509186

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